What are the late-stage symptoms of lymphoma?

The systemic symptoms of advanced lymphoma vary greatly depending on the type of disease and the stage of the disease. Some patients may have no systemic symptoms. Fever, weight loss, night sweats, etc. are more common in patients with symptoms, followed by loss of appetite, fatigue, itching, etc. Systemic symptoms are related to the age of onset, tumor range, body immunity, etc. Elderly patients, those with poor immune function or multifocal onset have significant systemic symptoms. The survival rate of patients without systemic symptoms is 3 times that of those with symptoms.

Specific symptoms include:

① Fever. The fever pattern is often irregular, and may be continuous high fever or intermittent low fever. A few may have periodic fever, which occurs in about 1/6 of Hodgkin's disease patients.

② Skin itching This is a more specific manifestation of Hodgkin's disease. Focal itching occurs in the area of ​​lymphatic drainage of the lesion. ③ Alcohol pain. 17%-20% of Hodgkin's disease patients experience pain in the lesion 20 minutes after drinking. The mechanism of alcohol pain is unknown.