What does HBsab positive mean, do you really know?

Hbsab is the abbreviation of hepatitis B surface antibody, which is a serum marker in the five-item hepatitis B test. This antibody has a certain protective effect on the human body. Once a positive test appears, it means that the hepatitis B virus already exists in the body and treatment must be received immediately, otherwise it is easy to cause other diseases. Under normal circumstances, it takes more than a month, or even longer, for Hbsab to turn negative.

1. Introduction to Hepatitis B Surface Antibody

Among the five serum markers of hepatitis B, antigen is the component of the virus itself, while antibody is the product of the body's immune response, and their clinical significance is different. Surface antibody (anti-HBs) is a protective antibody that often appears positive in the late stage of infection recovery, when the surface antigen (HBsAg) has turned negative for at least 1 month. Anti-HBs reaches its peak in June-December, then gradually decreases and turns negative within 10 years (sometimes it turns negative very quickly).

2. What does a positive hepatitis B e antibody mean?

Hepatitis B e antibody is one of the serological markers of human infection with hepatitis B virus. The English abbreviation of hepatitis B e antibody is anti-HBeAb. Hepatitis B e antibody positivity mainly occurs among asymptomatic hepatitis B surface antigen carriers and chronic hepatitis B patients. This indicates that viral replication in the body is inhibited to varying degrees, indicating that HBV in the blood is reduced and the infectivity is reduced.

Hepatitis B e antibody is another antibody produced against the hepatitis B virus E antigen itself. However, it should be pointed out that not all antibodies can protect the body as everyone imagines. In the hepatitis B virus antigen-antibody system, only the hepatitis B surface antibody has the ability to resist the hepatitis B virus in the human body. Other antibodies cannot effectively kill the hepatitis B virus. As long as there is hepatitis B virus in the body, treatment is necessary. If hepatitis B patients with positive e antibody are not treated in time, they may also turn into e antigen positive. Positive e antigen means that the hepatitis B virus has a strong replication ability and is more contagious, so patients should receive treatment as soon as possible.