What are the causes of ascites associated with ovarian cancer

Ovarian cancer patients often suffer from ascites, which not only aggravates the patient's physical and mental pain, but also makes the overall treatment of ovarian cancer even worse. So what factors are related to the occurrence of ascites?

1. Genetic factors

An important reason that cannot be ignored for ovarian cancer associated with ascites is the influence of genetic genes. About 25% of ovarian cancer ascites have a family history. Such ovarian cancer patients are 18 times more likely to develop ascites than those without a similar history. Moreover, ascites does not necessarily occur in the late stages of cancer. Hereditary ovarian cancer ascites is related to gene mutations. Women carrying this mutated gene have a lifetime risk of developing ovarian cancer ascites of up to 65%.

2. Age Factor

Ascites can vary with age. For the same type of ovarian cancer patient, the older the patient is, the higher the incidence of ascites is, especially in menopausal and postmenopausal women, while patients around 20 years old have less ascites; and the occurrence of ascites in patients with different types of ovarian cancer also presents different characteristics in age. Ascites is more common in patients with ovarian epithelial cancer after the age of 40, and gradually decreases after the age of 70. Ascites in germ cell tumors is more common in young women under 20 years old. ?

3. Fertility factors

In general, single women or women without children have a higher risk of ovarian cancer, and the risk of ascites in this group of people is about 60% higher than that of married patients. For patients who have had more pregnancies, the number of cases of ovarian cancer ascites decreases gradually, and the risk naturally decreases.

The reason for this phenomenon may be that the absence of ovulation during pregnancy has a protective effect on the ovaries.

4. Environmental factors

The occurrence of ascites caused by ovarian cancer is also related to the pollution of chemical and physical environment. People who are frequently exposed to talcum powder, heavy metals, radiation and asbestos have a greater chance of developing ascites caused by ovarian cancer. In developed countries, where heavy industry develops rapidly, the incidence of ascites caused by ovarian cancer is 3 to 5 times that of developing countries.