Sometimes people will feel a dull pain in their bladder, but the degree of pain is not exactly the same. It still depends on each person's actual situation. Some patients have very severe pain. If this is the case, it will affect the patient's normal life habits and directly cause symptoms of pathological pain, so it must be treated in time. 1. Based on pathological characteristics, pain can be divided into nociceptive pain and neuropathic pain (or mixed pain of the two types). Nociceptive pain is a response to noxious stimuli by intact nociceptors, and the perception of pain is associated with tissue damage. Normally, pain impulses are generated by nerve endings, and nerve fibers are responsible for transmitting the impulses. Spontaneous impulses can also occur when nerve fibers are damaged or the nervous system undergoes abnormal changes due to trauma or disease, and the resulting pain can be projected to the site of nerve origin, which is called neuropathic pain. 2. Depending on the duration and nature of pain, pain can be divided into acute pain and chronic pain. Chronic pain can be further divided into chronic non-cancer pain and chronic cancer pain. Acute pain is short-lived (less than 2 months) and usually occurs after a noxious stimulus. Acute pain recurrence is also often diagnosed as a recurrence of pain. Breakthrough pain is a specific type of acute pain that usually refers to a brief onset of pain above the original analgesic level in patients receiving chronic opioid therapy due to a sudden increase in pain intensity. If pain is not fully controlled in the initial stage, acute pain may develop into chronic pain, which may be due to pathological changes in the pain transmission pathway, thus becoming the cause of the pain. Chronic pain causes depression and anxiety in patients, takes a heavy toll on their body and mind, and severely affects their quality of life. It may persist without any clear cause or tissue damage. There are different opinions on the time limit of chronic pain. Most people define chronic pain as pain that lasts for 3 months without obvious tissue damage. Chronic non-cancer pain is significantly different from chronic cancer pain. For patients with cancer pain, pain relief depends on killing tumor cells or blocking pain transmission pathways. Most patients have a limited life expectancy and little consideration is given to drug dependence or possible long-term toxicity. Analgesia for patients with chronic non-cancer pain requires not only reducing the short-term and long-term toxicity of drugs as much as possible, but also preserving the patient's quality of life as much as possible. |
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