Brief analysis of the common causes of gallbladder cancer

As one of the more common malignant tumors, gallbladder cancer threatens the life and health of many people. What are the causes of gallbladder cancer ? Here are some common causes of gallbladder cancer.

Common causes of gallbladder cancer include:

(1) Cholelithiasis is a common cause of gallbladder cancer:

In foreign countries, 70%-90% of gallbladder cancer coexists with gallbladder stones. After gallbladder removal surgery, 1.5%-6.3% of cases of gallbladder cancer were found. It was also found that the larger the diameter of the stone, the higher the incidence rate. The incidence rates of stones with diameters <20-22mm and >30mm were 2.4 and 10 times that of stones with diameters less than 10mm, respectively. Some people believe that cholesterol and bile salts in bile can evolve into carcinogens such as methylcholine under the influence of infection and other factors (especially when infected by anaerobic bacteria Bacillus cereus). This may be one of the reasons for irritating the gallbladder mucosa and causing gallbladder cancer.

(2) Gallbladder adenoma and gallbladder adenomyosis:

Gallbladder carcinoma in situ and 19% of invasive carcinoma tissues contain adenoma components, which only reminds the relationship between the two; in recent years, many data have recognized that gallbladder adenoma is a precancerous lesion of gallbladder cancer. About 10%-30% of gallbladder adenomas can evolve into cancer, especially adenomas with a diameter greater than 12mm. Some data point out that the carcinoembryonic antigen expression of adenoma carcinoma is similar to that of gallbladder cancer, and the same antigen substances exist. The surface of gallbladder adenomyoma, which is limitedly covered with mucus-containing mucosa, may have mucus cell metaplasia areas, which are most likely to undergo malignant transformation. This is also a common cause of gallbladder cancer.

(3) Gallbladder polyps:

Gallbladder polyps can be divided into cholesterol polyps, non-cholesterol polyps, and polyp-type adenocarcinomas, which account for 50%-60%, 40%, and 10% of the total number of polyps, respectively. The latter may be adenoma-like, and 50% are accompanied by gallstones. It has been reported that in 90%-98% of gallbladder cancers, common polyps (the third type mentioned above) are mixed in with their cancerous foci, indicating that gallbladder polyps may have a certain relationship with the causes of gallbladder cancer.

The above is an introduction to the common causes of gallbladder cancer. I hope it will be helpful to everyone. Once you have gallbladder cancer, you must go to the hospital for treatment in time to avoid missing the best time for treatment.

For more information, please visit the gallbladder cancer disease special topic at http://www..com.cn/zhongliu/dna/ or consult an expert for free. The expert will then give a detailed answer based on the patient's specific situation.