What is the cause of prostate tumors?

With the change of living standards and habits, the incidence of prostate tumors is getting higher and higher. Therefore, we should understand the causes of prostate tumors so that we can better prevent prostate tumor diseases.

Prostate tumor is a common malignant tumor in elderly men. More than 95% of the diagnosed cases are between 45 and 89 years old, with an average age of 72 years old, and the incidence rate increases with age. In addition, according to the characteristics of prostate tumors, the use of androgens will accelerate tumor development and increase serum acid phosphatase, while the use of estrogens will slow down tumor growth and maintain serum acid phosphatase at a certain level, indicating that the incidence of prostate tumors is related to sex hormone metabolism.

The cause of prostate cancer has not been fully identified, and may be related to race, genetics, sex hormones, food, and environment. According to research, a large part (40%) is due to genetic gene mutations, and recent molecular biology research has also revealed a variety of chromosomal aberrations. The complex and interdependent relationship between these factors and environmental carcinogens (accounting for 60%) is not yet clear.

About 9% of prostate tumors and 45% of prostate tumors under the age of 55 are due to an inherited oncogene. Understanding these genes is undoubtedly extremely useful for understanding the carcinogenesis of prostate tumors. Recent reports have found that allele imbalance in the 23.2 segment of the long arm of chromosome 16 may be a tumor suppressor gene for familial hereditary prostate tumors. Another assumption is that the intensity of the response of epithelial cell androgen receptor to androgen is inversely proportional to the length of the CAG micro-repeat region of the 5 promoter co-catalyst region of the receptor gene. The shorter the length, the stronger the cell's response to androgen and the faster the cell grows. The length of CAG is shorter in both blacks and whites with cancer than in the control group. Obviously, the length of the CAG micro-repeat region of the androgen receptor has a potential relationship with the development of prostate tumors.

The above is a detailed introduction to the causes of prostate tumors. I hope it will be helpful to you. If you have other questions, you can come to our hospital for detailed consultation.

Prostate tumor: http://www..com.cn/zhongliu/qlx/qlxzl.html