Symptoms of pancreatic tumors

Pancreatic tumor is the most common tumor among malignant tumors. The early symptoms of pancreatic tumor are not obvious and the disease is only discovered during an accidental physical examination. Below we will introduce the symptoms of pancreatic tumor in detail, hoping to help you.

1. Digestive system symptoms. Abdominal pain is a common symptom, which occurs in more than 3/4 of patients. The pain is mild at first and gradually worsens. The early pain is wide and difficult to locate. It is a vague feeling of fullness, distension, dull pain or dull pain. Patients with acute onset have abdominal cramps or dull pain with a clear location. Tumors in the head of the pancreas can cause right upper abdominal pain, and tumors in the tail of the pancreas can cause left upper abdominal pain. Severe back pain is often caused by the tumor metastasis along the nerve sheath to the posterior abdominal nerve plexus. The mass of pancreatic tumor can compress the posterior abdominal nerve when lying on the back, which often aggravates abdominal pain. Therefore, the typical pain of pancreatic tumor is pain caused when lying on the back, or the pain is aggravated, especially at night, forcing patients to sit up or bend forward to relieve it. The pain has nothing to do with diet, defecation or gas. In addition to upper abdominal pain, a few cases complain of pain in the left or right lower abdomen, around the umbilicus or the whole abdomen, and even testicular pain, which can be easily confused with other diseases. The pain can radiate to the middle back, front chest and left shoulder blade. Symptoms of pancreatic tumors include diarrhea, nausea, vomiting, constipation, and gastrointestinal distension. Nausea and vomiting may be temporary or occur only when there is abdominal pain; if the tumor erodes the gastrointestinal tract, it may cause vomiting blood and black stools. Tumors of the pancreatic body and tail may be palpable as irregular, hard, and fixed masses of varying sizes. 90% of patients with pancreatic head tumors may have an enlarged gallbladder.

2. Systemic symptoms. Weight loss is one of the important clinical manifestations of this disease. 90% of patients have rapid and obvious weight loss. Some patients also have weight loss as the first symptom, especially patients with pancreatic tail tumors and pancreatic body tumors. The cause of weight loss may be related to factors such as decreased appetite, insufficient pancreatic secretion, and malabsorption. Jaundice is one of the main symptoms for diagnosing pancreatic tumors. Depending on the characteristics of the tumor site, different degrees of jaundice appear. 100% of papillary ampulla tumors have jaundice, even in the early stage; pancreatic body and tail tumors have no jaundice in the early stage, but in the late stage, the tumor spreads to the pancreatic head, or metastasizes to the common bile duct, lymph nodes, and liver, causing extrahepatic or intrahepatic bile duct obstruction, jaundice may occur. The nature of jaundice is obstructive, and it gradually deepens, showing dark yellow with green, accompanied by strong tea-like urine, clay stools, and skin itching. Once jaundice appears, it often does not subside. However, in some cases, jaundice may be temporarily alleviated or disappear due to factors such as the temporary disappearance of tumor inflammation and edema, the formation of bile-intestinal fistula, and necrosis and shedding of tumor tissue. Symptoms of pancreatic tumors include fever, which may be high, low, intermittent or irregular. In addition, this disease also has symptomatic diabetes, thrombophlebitis, anxiety, depression, insomnia and other mental symptoms.

3. Metastatic symptoms. Pancreatic tumors can directly infiltrate the wall of the common bile duct, or cause obstructive jaundice due to tumor compression in the early stage. As the tumor develops, the tumor adheres to the stomach, duodenum, large intestine and inferior vena cava, or infiltrates into the internal organs, and then infiltrates the superior mesenteric artery and portal vein, leading to portal hypertension and ascites. Tumors in the body and tail of the pancreas obviously develop into the retroperitoneum and compress the splenic artery, often causing splenomegaly and esophageal varices. The tumor extends posteriorly, compressing or eroding the celiac plexus, causing low back pain, and occasionally complicated by pancreatitis. Bone metastasis of the tumor can cause severe and continuous pain. Metastasis to the lungs and mediastinum can cause chest pain, cough, dyspnea and other symptoms. Bile stasis or metastasis to the liver can cause liver enlargement. Clavicular, axillary or inguinal lymph nodes can also swell due to tumor metastasis.

The above content mainly introduces the symptoms of pancreatic tumors in detail. I hope it can be helpful to you. If you have other questions, you can come to our hospital for detailed consultation.

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