What is the preferred treatment for idiopathic thrombocytopenic purpura?

Idiopathic thrombocytopenic purpura is a common hemorrhagic disease in clinical practice, which is a spontaneous bleeding. The first priority in the treatment of idiopathic thrombocytopenic purpura is to pay attention to care, especially care for bleeding, followed by the use of drugs and care.

1. Care for bleeding. When there is only slight skin bleeding, no special treatment is required, but you should pay attention to observe the condition. If bleeding continues or bleeding occurs in other parts of the body or organs, go to the hospital for treatment.

2. Mental preparation. The chronic type of disease has a longer course. Both the patient and his or her family should be fully prepared mentally and provide meticulous home care to minimize the inconvenience in the patient's life caused by the disease.

3. Drug application and care. Although glucocorticoids are effective in treating idiopathic thrombocytopenic purpura, long-term and large-scale use or sudden discontinuation of the medication can cause many serious adverse reactions. Therefore, the medication must be used strictly under the guidance and supervision of a doctor. Do not increase or decrease the dosage or stop taking hormone drugs on your own, and observe any of the following reactions at any time during the medication process. You can go to a local regular hospital for a consultation.

4. Splenectomy is one of the effective treatments for idiopathic thrombocytopenic purpura. The surgical indications are:

① Chronic ITP, active medical treatment for 6 months is ineffective.

② Patients with poor efficacy of adrenocortical hormones or those who need to be maintained at a higher dose (30-40 mg/d).

③ Those who are contraindicated in taking hormones or immunosuppression.

④51Cr labeled platelet examination. If the platelets are mainly retained in the spleen, the spleen efficiency can reach 90%. If they are retained in the liver, 70% of splenectomy will be ineffective. The effective rate of splenectomy can reach 70-90%, and the postoperative recurrence rate is 9.6-22.7%. The long-term effect is 50-60%.