What are the causes of bladder cancer

In recent years, bladder cancer has become one of the major diseases that endangers society and human health, and it has brought great pain and distress to humans. In order to reduce the incidence of bladder cancer, we humans should understand the causes of bladder cancer:

① People who work with long-term contact with aromatic substances, such as dyes, leather, rubber, painters, etc., may have a high incidence of bladder tumors.

② Smoking is also a factor that increases the incidence of bladder tumors. Recent studies have shown that smokers increase the metabolism of the carcinogenic substance tryptophan in their urine by 50%. When smoking stops, tryptophan levels return to normal.

③ Abnormal tryptophan metabolism in the body. Abnormal tryptophan metabolism can produce some metabolites, such as 3-hydroxy-2-aminoacetophenone and 3-hydroxy-o-aminobenzoic acid, which can directly affect the synthesis of RNA and DNA in cells. These metabolites are excreted into the bladder through the action of the liver and have carcinogenic effects after being acted on by β-glucuronidase.

④ Long-term local irritation of the bladder mucosa. Long-term local irritation of the bladder wall, such as long-term chronic infection, long-term irritation of bladder stones and urinary tract obstruction, may be factors that induce cancer. Glandular cystitis and mucosal leukoplakia are considered to be precancerous lesions that can induce cancer.

⑤ Drugs. Taking large amounts of phenacetine has been shown to cause bladder cancer.

⑥ Parasitic diseases

The above are the causes of bladder cancer. Expert Tips: If you have symptoms of disease, do not delay diagnosis and go to a regular hospital for treatment in time to avoid delaying the disease and causing serious consequences. If you have other questions, please consult our online experts or call for consultation.

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