Drugs for treating blood clots in the legs

Thrombosis is a very common disease. It can cause local inflexibility and even affect normal life. Leg thrombosis mainly occurs in middle-aged and elderly people. Leg thrombosis can cause inflexibility of the feet and inability to walk normally. Once the disease is discovered, it needs to be treated in time to be controlled. Otherwise, if it is serious, amputation may be required. So, what are the medications for treating blood clots in the legs?

Drug therapy is a common non-surgical treatment method, including thrombolytic therapy, anticoagulant therapy, antiplatelet drugs and vasodilators.

(1) Thrombolytic therapy: It is to use drugs with thrombolytic effect to dissolve blood clots, thereby relieving the blockage of the deep veins of the lower limbs and allowing the blood in the deep veins of the lower limbs to flow back smoothly.

(2) Anticoagulant therapy: It is the use of drugs with anticoagulant effects to prevent blood clots from continuing to spread and expand.

(3) Antiplatelet drugs: mainly used as auxiliary and maintenance treatment after the acute treatment of deep vein thrombosis of the lower limbs.

(4) Vasodilators: used to dilate small veins. Just like when the main highway is completely blocked, people will create some irregular paths on both sides of the trunk to solve the road traffic problem. These irregular paths trampled out are equivalent to side branch circulation. After using vasodilator drugs, the small veins are dilated, allowing these dilated small veins to partially or mostly replace the return of the deep veins of the lower limbs.

In the acute phase of deep vein thrombosis, intravenous thrombolytic drugs such as urokinase or streptokinase are first used. After one course of treatment, anticoagulant therapy is used instead and continued for 3 to 6 months. Especially for peripheral deep vein thrombosis of the lower limbs, surgical treatment is not recommended. For the treatment of central deep vein thrombosis of the lower limbs, many specialists mainly use non-surgical treatment, but half of the treatments are incomplete, often leaving some sequelae. However, drug treatment cannot improve long-term outcomes, and half of the patients will still suffer from sequelae of varying degrees.