Will jaundice occur if transaminase is high?

Newborns will develop jaundice soon after birth. Although this is a relatively normal phenomenon, when the neonatal jaundice is too excessive, it should also attract the attention of parents. There are many causes of neonatal jaundice. When the neonatal jaundice is too excessive, treatment is required. Therefore, correct treatment should be carried out according to the cause of jaundice to achieve a more ideal treatment effect.

Will high transaminase cause jaundice?

First: There are many causes of elevated transaminase levels, the most common of which are viral hepatitis, especially hepatitis B, as well as alcoholic, fatty, drug-induced, autoimmune, etc. Excessive fatigue and staying up late can also increase transaminase levels. This means that your liver is being damaged and must be treated as soon as possible.

Second: High transaminase usually reflects organic liver disease, which is released after liver cell necrosis. Generally, eating alone will not be of much help. You can go to the hospital to check your liver function and then use symptomatic medication.

Third: The transaminase level is significantly increased, accompanied by jaundice. Hepatitis tests have been done to rule out the possibility of hepatitis. The liver damage should be mainly caused by other liver diseases, such as non-viral hepatitis (drug-induced or toxic hepatitis, other serum hepatitis, liver space-occupying lesions, or jaundice and increased transaminase level caused by obstructive jaundice.

Causes of neonatal jaundice

Physiological jaundice:

It is a phenomenon unique to the neonatal period. Because the fetus is in a low-oxygen environment in the uterus, there is an overproduction of red blood cells in the blood. These red blood cells are mostly immature and easily destroyed. After the fetus is born, excessive bilirubin is produced, which is about twice that of adults. On the other hand, due to the immature liver function of the newborn, bilirubin metabolism is restricted, causing the newborn to experience jaundice for a period of time.

Breast milk jaundice:

It occurs due to breastfeeding and is a special type of pathological jaundice. Because breast milk contains the hormone pregnanediol, it can inhibit the activity of glucuronyl transferase in the liver of the newborn, so that the bilirubin in the blood cannot be metabolized and excreted in time, the concentration increases, and the newborn's skin and sclera become yellow.

Infectious jaundice:

It occurs when liver cell function is damaged due to viral infection or bacterial infection. Viral infections are mostly intrauterine infections, with cytomegalovirus and hepatitis B virus infections being the most common. Other infections include rubella virus, Epstein-Barr virus, toxoplasmosis, etc., which are relatively rare.