Symptoms of renal impairment

Renal function damage means that the patient has renal insufficiency. Such patients often have problems with renal function, and some complications caused by renal function are also relatively harmful. First of all, renal function diseases mainly include acute and chronic glomerulonephritis, as well as renal tuberculosis, chemical poisons and biological toxins, etc., which require special attention to receive reasonable treatment methods.

Whether renal insufficiency can be recovered and how to prevent it from worsening depends on every improvement of the patient during the treatment process. Simply answering the question of whether renal function failure can be recovered is bound to sound like nonsense. Here, I want to talk about several key points that determine whether renal insufficiency can be recovered:

1. Can renal insufficiency be restored? Key point 1 Causes of renal insufficiency:

The causes of renal insufficiency can be summarized as follows:

1. Kidney diseases: such as acute and chronic glomerulonephritis, pyelonephritis, renal tuberculosis, acute tubular degeneration and necrosis caused by chemical and biological poisons, kidney tumors and congenital kidney diseases.

2. Extra-renal diseases: such as systemic blood circulation disorders (shock, heart failure, hypertension), systemic metabolic disorders (such as diabetes) and urinary tract diseases (urinary stones, tumor compression), etc.

Generally speaking, when kidney disease is in the renal insufficiency stage, if the treatment measures are appropriate, renal insufficiency can be completely cured. However, if the renal insufficiency is caused by tumors and congenital kidney disease (such as polycystic kidney disease, renal cysts), any current medical treatment is helpless. The only way is to control the growth of the cyst and prevent it from recurring, so as to avoid the disease from worsening and affecting the survival of patients with renal insufficiency.

2. Can renal insufficiency be restored? The key point is to see the severity of renal insufficiency and whether effective treatment measures are taken:

Clinically, renal insufficiency is divided into four stages:

1. Compensatory stage of renal insufficiency: creatinine index is between 120umol/L-133umol/L, and the number of renal units decreases by about 20~25%. At this time, the kidney's ability to excrete metabolic products and regulate water, electrolytes and acid-base balance is still good, and blood creatinine and blood urea nitrogen are normal or slightly elevated.

2. Decompensated renal insufficiency (azotemia stage): creatinine index is between 133umol/L-442umol/L, renal units are reduced by 50~70%, renal concentrating function is impaired, nocturia or polyuria, anemia, fatigue, loss of appetite, nausea and mild general discomfort occur. Azotemia and increased blood creatinine and urea nitrogen are common.

3. Renal failure stage: The creatinine index is between 442umol/L and 707umol/L, the renal units are reduced by about 70% to 90%, the renal function is severely damaged, and there are obvious anemia and gastrointestinal symptoms such as nausea, vomiting, and decreased appetite. Serum creatinine and urea nitrogen increased significantly, acidosis, water and sodium retention, low calcium, high phosphorus and high potassium.

4. Uremia stage: The creatinine index is greater than 707umol/L, and the number of renal units is reduced by more than 90%. This stage is the late stage of chronic renal failure, manifested by multiple organ failure throughout the body, such as nausea and vomiting, irritability, increased blood pressure, palpitations, chest tightness, inability to lie flat, difficulty breathing, severe anemia, convulsions, and coma in severe cases. There are often hyperkalemia, hyponatremia, hypocalcemia, and hyperphosphatemia.

3. Can renal insufficiency be recovered? The key point lies in the treatment of renal insufficiency.

Renal insufficiency is a clinical syndrome that occurs in the late stages of various chronic renal diseases. Its main manifestations are persistent decline in renal function, retention of metabolites, disorders of water, electrolyte, acid and base balance, and complications of various systems.

The disease is divided into four stages according to the degree of renal function damage: compensated stage, decompensated stage, renal failure stage, and uremia stage.

Therefore, clinical improvement can be achieved through active treatment in the early stages. The increase in creatinine in chronic renal insufficiency is due to damage to the kidney's intrinsic cells. Renal fibrosis occurs, and normal renal units with filtration function are replaced by fibrous tissue, losing their detoxification function, causing toxins to accumulate in the body and cannot be excreted.