Is mania hereditary?

Patients with mania are often more manic and have difficulty controlling their emotions. Therefore, patients with mania are most susceptible to emotional fluctuations and affect the people around them. This is because mania involves mental factors, psychological factors, disease factors, etc., and it is not ruled out that it is related to genetics.

Pathological etiology

1. Genetic factors.

2. Physical factors: The main characteristics of cyclothymic personality are sociability, cheerfulness, broad interests, activeness, easy excitement and optimism, but also easy to become anxious and melancholy. Patients with mesomorphic skeleton, well-developed muscles and abundant connective tissue are more likely to suffer from the disease than those with ectomorphic body with slender and delicate physique.

3. Abnormal functions and metabolism of central nervous system mediators.

(-) Abnormal function of the central noradrenergic system.

(B) Abnormal function of the central 5-HT system.

(III) Multiple amine metabolism disorder hypothesis.

4. Neuroendocrine dysfunction.

4. Mental factors:

The onset of manic-depressive psychosis may be related to mental stimulation factors, but they can only be regarded as inducing factors.

Disease diagnosis

1. Adolescent Schizophrenia

It is common in clinical practice that adolescent schizophrenia is misdiagnosed as mania, and the opposite situation also occurs from time to time. This is because schizophrenia can also have a cyclical course, and the clinical manifestations may also include motor excitement. However, after several episodes of schizophrenia, the cyclical course gradually becomes less obvious, and it becomes a chronic progressive course. Although there is excitement and agitation in the clinical phase, the emotions are not relaxed and happy, but moody, and the behaviors are mostly impulsive. Clinically, some bipolar patients do have psychotic characteristics that are inconsistent with their mood, but they last for a short time and prolong with the course of the disease.

2. Toxic psychosis Poisoning with certain drugs such as corticosteroids, isoniazid, and adenomyosis can cause manic states.

Based on the medication history, medication time, dosage and onset relationship, the gradual improvement after stopping or reducing the medication can be used for identification. Toxic psychosis is often accompanied by varying degrees of consciousness disorders.

3. Organic brain mental illness

For example, paralytic dementia and senile psychosis may present with manic state, but they are often accompanied by intellectual impairment, and the emotions are not high, but mainly euphoric. A detailed medical history, physical and neurological examinations are helpful for differentiation.

4. Mental disorders caused by physical illness

Hyperthyroidism may cause a hypomanic state, but the emotions are not truly elevated. Instead, anxiety and mood instability are the main symptoms, accompanied by symptoms and signs of primary physical illness.