Dosage of Ceftriaxone Sodium for Injection

Ceftriaxone Sodium for Injection is an antibiotic drug that is mainly used to treat some infectious diseases. Like other western medicines, cefotaxime sodium for injection can cause allergic reactions, so an allergy test should be done before using the medicine to prevent allergic reactions, which may even threaten life. Ceftriaxone sodium for injection is generally suitable for adults. Intramuscular injection is not allowed in infants and young children, and the elderly should reduce the amount of drug injection appropriately. Having said so much, are you curious about how to use ceftriaxone sodium for injection? Let’s follow me to learn more about it in detail!

1. Category

Chemicals and Biological Products>>Antimicrobial Drugs>>Antibacterial Drugs>>Antibiotics

(II) Characteristics

This product is white to pale yellowish white crystalline powder.

3. Indications

It is suitable for pneumonia and other lower respiratory tract infections, urinary tract infections, meningitis, sepsis, abdominal infections, pelvic infections, skin and soft tissue infections, reproductive tract infections, bone and joint infections, etc. caused by sensitive bacteria. Ceftriaxone can be used as an alternative drug for children with meningitis.

(IV) Usage and Dosage

Adults: 2-6 g per day, divided into 2-3 times for intravenous injection or intravenous drip; for patients with severe infection, 2-3 g every 6-8 hours, and the maximum daily dose shall not exceed 12 g. For the treatment of uncomplicated pneumococcal pneumonia or acute urinary tract infection, 1 g every 12 hours.

For newborns aged 7 days or less, take 50 mg/kg every 12 hours; for newborns aged 7 days or more, take 50 mg/kg every 8 hours. For patients with meningitis, the dose can be increased to 75 mg/kg every 6 hours, all administered intravenously.

Patients with severe renal impairment should reduce the dosage of this product appropriately. When the serum creatinine value exceeds 424μmol/L (4.8mg) or the creatinine clearance rate is lower than 20ml/min, the maintenance dose of this product should be halved; when the serum creatinine exceeds 751μmol/L (8.5mg), the maintenance dose is 1/4 of the normal amount. For patients who need hemodialysis, take 0.5 to 2 g per day. However, an additional dose should be given after dialysis.

(V) Adverse Reactions

The incidence of adverse reactions is low, about 3% to 5%.

(1) Skin rash, drug fever, phlebitis, diarrhea, nausea, vomiting, loss of appetite, etc.

(2) Mild increase in alkaline phosphatase or serum aminotransferase, temporary increase in blood urea nitrogen and creatinine, etc.

(3) Leukopenia, leukocytosis, or thrombocytopenia are rare.

(4) Headache, numbness, dyspnea and facial flushing may occur occasionally.

(5) A very small number of patients may develop mucosal candidiasis.