The birth of a baby with Down syndrome is a painful thing for the baby and the family, so it is generally recommended that pregnant women actively undergo prenatal examinations and Down syndrome screening after pregnancy. At the same time, they should also understand the causes of the birth of babies with Down syndrome. Only when we have a more scientific understanding of this knowledge can we take preventive measures and reduce the birth rate of Down syndrome babies. 1. Genetic factors Causes of Down syndrome: Genetic factors are the main cause. Specific manifestations: 1. 10% of Down syndrome is caused by extra chromosomes from the father. 2. If a pregnant woman gives birth to a child with Down syndrome, the chance that the second child will have the disease is higher than the average person. Specific analysis: Down syndrome is a birth defect disease caused by genetic factors, that is, it is affected by the parents' own genetic genes and is a factor that cannot be changed by current human medicine. Recommendation: 1. However, reasonable genetic counseling, chromosome identification before conception, strengthening maternal health care, and reducing the pregnancy rate of older pregnant women are effective measures to reduce the disease. Clinicians can provide health advice based on the child's parents' previous pregnancy and delivery history, strengthen perinatal care when necessary, actively seek prenatal diagnosis, and avoid the birth of children with developmental defects as much as possible. 2. Teratogens and diseases Causes of Down syndrome: teratogens and diseases. Specific analysis: 1. Teratogens in the environment such as radiation, benzene, pesticides, and certain drugs such as sulfonamides can cause chromosomal aberrations. 2. If a woman has been exposed to radiation in the abdomen before or in early pregnancy, or has been exposed to other teratogens multiple times, or has had a viral infection, the chance of her children having Down syndrome will increase significantly. 3. Parents’ age at the time of pregnancy The cause of Down syndrome: the age of the parents when they become pregnant. The older they are, the greater the chance of having a child with Down syndrome. Specific analysis: 1. The age of pregnant women is the main factor affecting the incidence rate. As the mother's age increases, the chance of her children developing the disease also increases. 2. If the mother is under 25 years old, the rate of Down syndrome children is 1/2000; if the mother is between 35 and 39 years old, the rate is 1/50; if the mother is over 40 years old, the rate is 1/20. 3. In other words, if you get pregnant and give birth after the age of 40, no matter which birth order you have, the chance of giving birth to a baby with Down syndrome is 100 times higher than before the age of 25. |
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