How should fungal dermatitis be treated?

Fungal dermatitis is actually a disease that can occur in any part of the body, so everyone must pay attention to it. Fungal dermatitis can cause varying degrees of damage to the patient's skin, such as breakage, ulceration, itching, etc., and the patient himself will also feel intense discomfort. When fungal dermatitis is discovered in the early stages, it can be treated with common medications.

Basic Introduction

Fungal skin diseases, also known as dermatophyte diseases, refer to a large class of infectious diseases of human skin and skin appendages such as mucous membranes, hair and nails caused by pathogenic fungi. Dermatophytes are the main pathogens of fungal skin diseases, including Trichophyton rubrum, Trichophyton gypseum, Epidermophyton floccosum, Trichophyton verrucosum, Microsporum and so on. The common characteristics of these diseases are: high incidence, contagiousness, and easy recurrence or reinfection. Especially unreasonable and non-standard treatments will cause repeated attacks and repeated treatments, greatly affecting the patient's quality of life. Fungi like warm and humid weather, and the most suitable temperature for shallow fungi is 22℃~28℃. When conditions on human skin are suitable for fungal growth and reproduction, ringworm is likely to occur. For example, some people sweat easily and their skin is easily damp. If they are not wiped clean and kept dry in time, they are prone to fungal infection and develop tinea versicolor and other ringworm diseases. If they wear pants that are too tight, too thick and not breathable and sit in the office for a long time, they are prone to tinea cruris and other ringworm diseases. If they often wear rubber shoes, leather shoes, and sports shoes, if the air permeability is poor, the humidity and temperature of the feet will increase. If the skin is not clean, it is very easy to develop tinea pedis and other ringworm diseases. Moreover, if there is a type of ringworm on the body, it can spread through itself and cause ringworm to occur in other parts of the body.

Systemic treatment

(1) Ketoconazole: This drug is now mostly taken orally to replace griseofulvin. Ketoconazole is a synthetic broad-spectrum antifungal imidazole drug. Its antifungal mechanism is to inhibit the synthesis of ergosterol, an important component of fungal cell membrane, causing the fungal cell membrane to lose its normal function, resulting in increased membrane permeability, and finally causing the fungus to degenerate or even die. According to clinical practice, this medicine has a good effect on superficial fungal diseases.

Indications: Mainly used for tinea capitis, followed by systemic tinea corporis, severe tinea cruris and onychomycosis.

Contraindications: Abnormal liver function. This drug is contraindicated in pregnant and lactating women.

Dosage: Adults, 200 mg, once a day. For children weighing less than 20 kg, take 50 mg once a day; for children weighing 20-40 kg, take 100 mg once a day; for children weighing more than 40 kg, take the adult dose.

(ii) Other imidazole drugs: Itraconazole has an antifungal potency 5 to 10 times that of ketoconazole and is the minimum dose used to treat dermatophytes.

Topical treatments

For superficial fungal diseases that do not involve the hair or nail plate, local therapy can be effective, but it requires patience and persistence in applying the medicine for a long time. There are two groups of drugs commonly used.

(I) Special external medicine: You can choose the special medicine Kexuanling liquid and apply it to the affected area.

(ii) Specific broad-spectrum antifungal agents: The most widely used group all have a common imidazole ring, i.e., imidazole drugs such as fioconazole, miconazole, oxiconazle, econazole, ketoconazole, bifonazole and clotrimazole, which are often made into 1-2% creams for clinical use.