What is the reason for a high neutrophil ratio

There are many items in the test report of routine blood test. Doctors usually focus on three data: white blood cells, lymphocytes, and neutrophils. These three are particularly important reference standards. People who often check laboratory tests may have noticed that there is an indicator value behind the routine blood test report, which is the neutrophil percentage. Through the test report, we can clearly see which test results are not within the normal proportion range, whether they are high or low, which are all abnormal manifestations. If the test report shows that the neutrophil ratio is high, what is going on and what is the reason? Experts say that the reason for a high neutrophil percentage is generally bacterial infection. Let us find out.

As we all know, white blood cells are the body's defense "guards" that specifically help us resist foreign invasions such as bacteria and ensure that our health is not destroyed. However, among these guards, there is a team of "elite soldiers" that needs more attention, and that is neutrophils. Neutrophils are always at the forefront of the battle and play a vital role in the human immune system. For doctors, when looking at blood test reports, they should not only check whether the white blood cell count is lower than the normal value, but also pay attention to the number of neutrophils.

Neutrophil monitoring is a must-check item in routine urine examination. Neutrophils affect the function of our immune system, and whether they are normal has important reference significance.

1. What is the normal value of neutrophils?

Normal reference values ​​for neutrophils:

Reference value: 0.40～0.75(40%～75%);(1.80～6.30)×109/L.

2. Significance of neutrophil monitoring

1. Increase

Acute and suppurative infections (furuncles, abscesses, pneumonia, appendicitis, erysipelas, sepsis, visceral perforation, scarlet fever, etc.), various poisonings (acidosis, uremia, lead poisoning, mercury poisoning, etc.), tissue damage, malignant tumors, acute massive bleeding, acute hemolysis, etc.

2. Reduce

It is seen in infectious diseases such as typhoid, paratyphoid, measles, influenza, chemotherapy, and radiotherapy. Certain blood diseases (plastic anemia, agranulocytosis, myelodysplastic syndrome), hypersplenism, autoimmune diseases, etc.

3. Reasons for high neutrophil percentage

What are neutrophils? In Wright-stained blood smears, the cytoplasm of neutrophilic granulocytes is colorless or very light red, with many diffusely distributed tiny (0.2 to 0.4 microns) light red or light purple characteristic granules. The cell nucleus is rod-shaped or 2-5 lobed, with lobes connected by filaments. The surface of its particles is covered with a layer of membrane and can be divided into types 1 to 4. The particles contain myeloperoxidase, acid phosphatase, phagocytin, lysozyme, β-glucuronidase, alkaline phosphatase, etc. Neutrophils have chemotactic, phagocytic and bactericidal effects.

Experts say that if the white blood cell count is higher than 10,000, the inflammation is severe and you can use anti-inflammatory drugs or intravenous drips. If the white blood cell count is lower than 4,000, it means that the resistance is relatively low and antipyretics should be used less. If the percentage of lymphocytes is high, it is a viral infection; if the percentage of neutrophils is high, it is a bacterial infection. White blood cells are mainly neutrophils. If the neutrophil count is high, the white blood cell count is generally also high. This is commonly caused by infection, and a common cold will cause an increase.

Colds can increase the percentage of neutrophils

If both the white blood cell count and the neutrophil percentage are high, it indicates a bacterial infection; if the white blood cell count is low and the lymphocyte percentage is high, it is a viral infection; if the white blood cell count is normal or low and the neutrophil percentage is high, it may be both a viral and a bacterial infection. Of course, this is a basic judgment method, and the specific situation still needs to be determined by a doctor.