What diseases is photodynamic therapy suitable for?

Photodynamic therapy is a new technology for treating diseased tissues. It treats skin diseases through photodynamic methods and Ella photodynamic methods. Photodynamic therapy can effectively treat human skin diseases, skin cancer, or malignant tumors. It is not only simple and convenient to operate, but also very fast in treating diseases. It is a new method for treating skin diseases. Photodynamic therapy can effectively treat body genital warts, skin acne, etc., quickly remove skin necrosis and diseases, and quickly achieve the purpose of cure. Learn more about how this disease can be treated with photodynamic therapy.

Principle/Photodynamic Therapy

Photodynamic therapy

The photosensitizer is injected into the human body, and after a certain period of time, the lesion site is irradiated with light of a specific wavelength. Through a series of photochemical and photobiological reactions, singlet oxygen and/or free radicals are generated with the participation of molecular oxygen, which oxidatively destroy various biological macromolecules in tissues and cells, causing irreversible damage to abnormally proliferating cells and ultimately leading to cell death, thus achieving the therapeutic purpose.

Indications/Photodynamic Therapy

1. Precancerous skin diseases and skin malignancies such as actinic keratosis, basal cell carcinoma, and squamous cell carcinoma; 2. Treatment of non-malignant skin diseases such as condyloma acuminatum, vascular malformations, and acne vulgaris.

Photodynamic therapy

1. Medical staff will prepare fresh liquid medicine for use during treatment. 2. Apply fresh medicine to the affected area for 3 hours and perform local sealing according to the specific situation. 3. Irradiate the local lesion with red light, and the irradiation time is usually 20 minutes.

Adverse reactions/photodynamic therapy

The most common adverse reaction is local tingling pain during illumination, which most patients can tolerate or will be relieved on their own later, and generally no special treatment is required. Advise the patient not to be overly nervous. For those with obvious pain, apply "compound lidocaine cream" topically or notify the doctor for other further special treatments.

Cost/Photodynamic Therapy

1. The cost of the drug: Aminolevulinic acid hydrochloride (ALA) is more than 800 yuan per bottle. For patients with condyloma acuminatum whose area is not very large, use 1 tube for each treatment. If the area is large, increase the dosage. 2. The treatment cost is about 300 yuan per spot, and the general local illumination time is 20 minutes. 3. Treatment is usually once a week, lasting about half a day; 3 times is a course of treatment.

Precautions/Photodynamic Therapy

1. Genital warts in special areas (such as warts occurring around the urethral orifice, inside the urethra, and around the openings of vulvar glands) can be directly treated with photodynamic therapy, which has good efficacy and less recurrence. 2. For patients with repeated recurrences after local carbon dioxide laser or cryotherapy, local photodynamic therapy is recommended 2 to 3 times. 3. After conventional treatment, you can choose photodynamic therapy 2 to 3 times for consolidation treatment to prevent recurrence. 4. For larger warts, it is recommended to first use carbon dioxide laser or freezing to remove the large warts, and then choose photodynamic therapy. This can reduce the cost of treatment and shorten the treatment time. 5. Currently, no treatment can absolutely prevent the recurrence of genital warts. Generally, after three times of photodynamic therapy, the recurrence rate of warts is less than 10%.