What are the symptoms of Behçet's syndrome?

Behcet's syndrome is a relatively rare immune system disease that causes autoimmune problems and then leads to systemic vasculitis. Patients will have more obvious symptoms, such as recurrent oral ulcers, uveitis, and genital ulcers. After such symptoms appear, patients must pay attention and undergo corresponding examinations in a timely manner.

Behçet's disease (Behçet / Behçet's disease), also known as Behçet's syndrome, Morbus Behçet, Behçet-Adamantiades syndrome, and Behçet's syndrome, is called "Silk Road disease" because it is common in Silk Road countries. It is a rare microvascular systemic vasculitis of the immune system that can cause various ulcers and eye vision problems. It is more common in young people aged 20 to 40.

Basic symptoms

The main symptoms of Behçet's disease are recurrent oral ulcers and aphthous triple syndrome, recurrent genital ulcers and uveitis.

Skin and mucous membranes

Almost all patients have some form of painful oral mucosal ulcers, aphthous ulcers, or nonscarring oral lesions. Oral lesions are similar to those found in inflammatory bowel disease and can be recurrent. Painful genital ulcers usually form around the anus, vulva, or scrotum and cause scarring in 75% of patients. In addition, patients may present with erythema nodosum, a pustular vasculitis that invades the skin and lesions that resemble homologous chromosomes.

Vision System

Inflammatory eye disease develops early in the disease and in some cases has resulted in 20% loss of vision. Damage to the visual system can take the form of anterior uveitis, posterior uveitis, or retinitis. Anterior uveitis presents with eye pain, conjunctival injection, hypopyon, and decreased vision. Meanwhile, posterior uveitis presents with painless visual loss and visual field floaters. In Behcet's disease, a rare form of retinal vasculitis involving the eye occurs, in which vision may be painlessly decreased with floaters and visual field loss. Optic atrophy has been identified as the most common cause of visual impairment. Behcet's disease can cause primary or secondary optic nerve damage. Papilledema, a result of venous sinus thrombosis and retinal atrophy, has been identified as a secondary cause of optic nerve atrophy in Behcet's disease.