What is the normal level of glycosylated hemoglobin?

There is a standard value for glycosylated hemoglobin. If the glycosylated hemoglobin is too high or too low and not within the normal range, it means that there are indeed some disease conditions in the body. For normal conversation, the glycosylated hemoglobin value is 6.1 to 7.9.

1. The three standards for meeting blood sugar standards are fasting blood sugar, blood sugar 2 hours after a meal and glycosylated hemoglobin. Many diabetic patients only pay attention to fasting blood sugar and 2 hours after meal, but ignore the detection of glycosylated hemoglobin. In fact, if only fasting and postprandial blood sugar levels meet the standards but glycated hemoglobin is not well controlled, it proves that blood sugar control is still not up to standard.

2. Clinical research generally uses the normal value of glycosylated hemoglobin as the standard: 6.1-7.9. That is to say, as long as the normal value of the person examined is maintained within this range, the normal value standard can be determined.

3. Glycated hemoglobin is the product of the combination of hemoglobin and glucose in red blood cells. It can reflect the blood sugar level in the three months before blood collection. It is currently the most effective and reliable indicator to reflect the quality of blood sugar control. Diabetic patients should take glycated hemoglobin ≤ 7.0% as one of the treatment criteria. The standard can be slightly relaxed for the elderly (7.0%-7.5%). Young and middle-aged people should control glycated hemoglobin at ≤ 6.5% or lower. For every 1% decrease in glycated hemoglobin, diabetes-related complications can be reduced by 20%.

4. Only when fasting blood sugar is controlled between 3.9-6.1 mmol/L, 2-hour postprandial blood sugar is controlled between 7.0 mmol/L, and glycosylated hemoglobin is controlled below 6.5%, can the ideal control target be achieved. That is, not only the fasting hyperglycemia in the basal state but also the postprandial hyperglycemia in the load state should be controlled. Only when these two blood sugar levels are well controlled can glycosylated hemoglobin be reduced to the ideal level, thereby delaying and preventing the occurrence of various complications.

5. There are many methods for detecting glycosylated hemoglobin, the commonly used ones are microcolumn ion exchange chromatography, affinity chromatography, high pressure liquid chromatography, immune agglutination, ion capture method, electrophoresis, etc. The main manufacturers include SD10 and Primus from Bio-Rad in the United States, G7 from TOSOH in Japan, DREWSCIENTIFIC in the United Kingdom, DCA Vantage from SIEMENS in Germany, Nycocard Reader II from Nycocard in Norway, etc.