How to treat appendix mucinous tumor

How to treat appendix mucinous tumor

Appendiceal mucinous neoplasm is a very scary disease because it is a relatively rare low-grade malignant tumor. Once this disease occurs, the patient's survival rate will be very low, and the patient may even lose his life before receiving treatment. So how should appendiceal mucinous neoplasm be treated?

Appendiceal mucinous carcinoma (also known as appendiceal cystadenocarcinoma) is a type of appendiceal mucinous cyst. Appendiceal mucocele is not very rare in clinical practice, and 75-85% of them are benign. However, appendiceal cystadenocarcinoma is extremely rare, with literature reporting only 10% of appendiceal mucocele. Its clinical diagnosis is very difficult. Even during rapid frozen section examination, due to the vigorous mucus secretion of the tumor and the relatively small number of tumor cells, it is difficult for pathologists to determine whether it is benign or malignant. Because there may be no clinical symptoms, the preoperative misdiagnosis rate is almost 100%. A second operation was performed after postoperative pathology confirmed it to be cancer.

Appendiceal mucocele is a rare disease in which the appendix becomes cystic and has mucus accumulation in the cavity. The cause of this disease is still unclear. Some scholars believe that it is caused by proximal obstruction of the appendix, while others believe that this disease is a new tumor of the appendix. The detection rate of this disease during appendectomy is 0.07% to 0.3%. It is more common in women, with a male-to-female ratio of 1:3. Due to the atypical symptoms and medical history of this disease, approximately 25% to 50% of patients are diagnosed during surgery. The main symptoms and signs are abdominal pain and abdominal mass. The main diagnostic methods for appendix mucocele include X-ray, barium enema, B-mode ultrasound and CT examination, but the above examinations can only indicate the possibility of the disease from the side and it is difficult to make a clear diagnosis.

Plain X-rays may show calcification at the edge of the cyst, and barium enema may show that the appendix is ​​not visualized or the ileocecal region is filled with defects or displaced by external pressure. B-mode ultrasound is the main diagnostic method for this disease, which is relatively simple and quick. CT scans can not only locate the cyst, but also understand the relationship between the cyst and surrounding tissues, and assist in diagnosing the source of the cyst.

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