What are the treatments for brain glioma

For many patients, the most common treatment for glioma is surgery, and it is also the preferred way to treat malignant tumors. However, this method cannot completely cure the disease, and radiotherapy and chemotherapy are required in the later stages to prolong the patient's life.

1. Surgical treatment is the first choice for treating brain tumors. This is because glioma is a malignant tumor and can only be completely eliminated through surgical resection. There is generally no possibility of cure for patients with glioma, and treatment can only prolong life. The second is radiotherapy, which is also an important method for treating brain glioma. However, radiotherapy will damage normal brain cells, causing the patient's body to gradually become weak and unable to withstand subsequent treatment. In recent years, the application of ginsenoside Rh2, an auxiliary drug for radiotherapy and chemotherapy, has played a role in enhancing efficacy and reducing toxicity, thereby improving the clinical radiotherapy and chemotherapy effects of brain glioma.

2. Clinical treatment data show that the above treatment methods are not satisfactory for the treatment of brain glioma. How to find a more effective means to treat or even cure brain glioma is the lifelong goal of many medical workers. After a large number of experimental studies, experts have found that the effects of drugs for treating gliomas are unsatisfactory. One of the main reasons is that they have difficulty penetrating the blood-brain barrier and have difficulty reaching the lesion site. Solutes in the blood must pass through the endothelial cells of the brain capillaries to reach the brain tissue. The endothelial cell membrane is a bilayer membrane structure based on lipids, which is lipophilic and allows fat-soluble substances to pass easily. Therefore, the lipid solubility of solutes in the blood determines the ease and speed with which they pass through the barrier. Solutes with higher lipid solubility pass through the barrier more quickly into brain tissue.

3. Since ginsenoside Rh2 is highly fat-soluble, has few hydroxyl groups, and is also a small molecule, it can easily pass through the lipophilic endothelial cell membrane to reach the brain tissue and exert its tumor-inhibiting effect more quickly. Therefore, compared with many drugs for treating glioma, ginsenoside Rh2 has the great advantage of being able to penetrate the blood-brain barrier, with high bioavailability and good absorption.