What should I pay attention to when taking Metronidazole Sodium Chloride Injection?

When it comes to metronidazole sodium chloride, many people may be speechless because it is relatively unfamiliar and they don't know much about it. In fact, it is mainly used for various infections caused by anaerobic bacteria, such as common gastrointestinal infections. Digestive tract infections, etc. can be treated with metronidazole sodium chloride injection. So, what kind of substance is metronidazole sodium chloride? Next, let us all follow the editor to learn about it.

Metronidazole has a strong antibacterial effect on most anaerobic bacteria, but has no effect on aerobic bacteria and facultative anaerobes. The antibacterial spectrum includes Bacteroides fragilis and other Bacteroides, Fusobacterium, Clostridium perfringens, Eubacterium, Veillonella, Peptococcus and Peptostreptococcus, etc. Actinomycetes, Lactobacillus and Propionibacterium are resistant to this product. Its bactericidal concentration is slightly higher than the inhibitory concentration. This product can also inhibit the redox reaction of amoeba and cause the nitrogen chain of the protozoa to break. Its functions are as follows.

1. This product can inhibit the metabolism of warfarin and other oral anticoagulants, enhance their effects, and cause prolongation of prothrombin time.

2. The simultaneous use of drugs that induce liver microsomal enzymes, such as phenytoin sodium and phenobarbital, can enhance the metabolism of this product, reduce the blood concentration of the drug, and slow down the excretion of phenytoin sodium.

3. The simultaneous use of drugs such as cimetidine that inhibit the activity of liver microsomal enzymes can slow down the metabolism and excretion of this product in the liver and prolong its serum half-life. The dosage should be adjusted according to the results of blood drug concentration determination.

4. This product interferes with the metabolism of disulfiram. When the two are used together, patients may experience mental symptoms after drinking alcohol. Therefore, patients who have used disulfiram within 2 weeks should not use this product again.

5. This product can interfere with the results of aminotransferase and LDH determination, and can reduce the levels of cholesterol and triglycerides.

The above is an introduction to metronidazole sodium chloride. I hope it can be of some help to patients. However, the editor recommends that you should never take medicine without confirming the disease. It is best to go to the hospital to confirm. When taking medicine, don’t think that taking more will make you get better faster. That is a wrong idea. You must follow the doctor’s instructions and drink more water.