Methods for corticotroph adenoma

Corticotroph adenoma is a disease and is considered a tumor. Of course, this type of tumor is benign, but it still needs attention. Because adrenocorticotropic hormone cell adenoma has the possibility of becoming cancerous, anyone who has this disease must be extremely vigilant, otherwise the damage to the body will be very serious and may even be life-threatening.

1. Disorders in fat metabolism and abnormal distribution: obvious centripetal obesity, moon face, buffalo hump, supraclavicular fat pad, and relatively thin limbs.

2. Abnormal protein metabolism: catabolism is greater than anabolism, resulting in thin skin, capillary dilation, sanguineous constitution, and purple lines on the skin. Muscle weakness, muscle atrophy, poor wound healing and infection. Osteoporosis, back pain, and susceptibility to pathological fractures.

3. Abnormal glucose metabolism: leading to abnormal glucose tolerance (75%) and diabetes (8%-10%).

4. Water and electrolyte metabolism disorders: hypokalemia, hypochloremia, and hypernatremia. Severe cases may lead to hypokalemic alkali poisoning, which requires emergency treatment. Water and sodium retention can cause hypertension, with an incidence rate of 80%-90%.

5. Effects on gonadal function: Excessive cortisol inhibits pituitary gonadotropin. 71%-87% of female patients experience decreased libido, oligomenorrhea, amenorrhea, galactorrhea, and infertility; about 20% of male patients experience decreased libido, impotence, decreased sperm count, and testicular atrophy. The secondary increase in adrenal cortex male hormones can lead to acne (mostly on the face, chest and back), increased vellus hair in women, beard growth, and enlarged Adam's apple.

6. Other manifestations: Some patients have mental abnormalities, depression is the most common. If the disease occurs before puberty, it will seriously affect growth and development.

7. Late-stage patients often die from complications of cardiovascular and cerebrovascular diseases, respiratory diseases and infectious diseases.

For adrenocorticotroph cell adenomas, clinical treatment options need to be considered. Of course, for people in this situation, it is recommended to go to the hospital for examination immediately. In the hospital, the most commonly used method of treating the disease is surgery, followed by conservative treatment.