What are the symptoms of neuromuscular atrophy

Many people are unwilling to accept the symptoms of neuromuscular atrophy, because after the symptoms appear, it will seriously affect their health, and if they are not treated as soon as possible, it will cause greater harm to their body. Therefore, many patients with neuromuscular atrophy want to fully understand what the symptoms are. The following is a detailed introduction so that you can have a comprehensive understanding.

Symptom 1: Neurogenic muscular atrophy: caused by lower motor neurons and their damage. When the anterior horn cells and brainstem motor nerve nuclei are damaged, muscle atrophy is distributed segmentally, more common in the distal limbs, and is symmetrical or asymmetrical, without sensory impairment. Fasciac tremors often occur, and the degree of muscle strength and tendon reflexes is related to the degree of damage. Electromyography showed muscle fiber fibrillation potentials or high-amplitude motor unit potentials. Biopsy showed muscle atrophy and thinning. Microscopically, there are fascicular atrophic changes.

Symptom 2: Myogenic atrophy: caused by diseases of the muscles themselves. Atrophy is not distributed according to nerves, and is often proximal, with symmetrical muscle atrophy of the pelvic girdle and shoulder girdle, and in a few cases distal. Accompanied by muscle weakness, without muscle fiber tremor and sensory disturbance. Serum creatine phosphokinase, lactate dehydrogenase, aspartate aminotransferase, phosphoglucomutase, aldolase, etc. were all elevated to varying degrees, with creatine phosphokinase being the most sensitive. The characteristic change of electromyography is the appearance of short-duration multiphasic potentials.

Cause 2: Primary or genetically related peripheral nerve diseases, such as progressive Charcot-Marie-Schmidt-Joint disease, hereditary hypertrophic interstitial neuropathy, amyotrophic ataxia, multiple neurofibromatosis, hereditary ataxia polyneuropathy, familial hereditary Charcot-Marie-Schmidt-Joint disease syndrome, familial recurrent compressive peripheral nerve palsy, familial recurrent peripheral neuropathy, hereditary interstitial spondylitis neuropathy, etc.

The above content introduces in detail what are the symptoms of neuromuscular atrophy? For many patients with this disease, don’t wait. In order not to affect your health, it is best to go to the hospital for a comprehensive examination. Through a comprehensive examination, choose the best treatment method. After a period of treatment, you can control the disease as soon as possible to avoid serious harm to your body.