What is gastrointestinal stromal tumor

Gastrointestinal stromal tumors refer to a special type of tumor that originates from the digestive tract, usually in the stomach or small intestine. It is a relatively rare tumor, but it occupies an important position in digestive tract tumors. The formation of gastrointestinal stromal tumors is closely related to a mutation in a gene called c-KIT, which causes cells to grow uncontrollably and form tumors.

The symptoms of this type of tumor may not be obvious and are often ignored. Some patients may experience abdominal discomfort, abdominal pain, or indigestion. Some people may develop anemia due to bleeding from the tumor, which manifests as fatigue and pale complexion. When the tumor is large, it may cause intestinal obstruction, at which time the patient will feel severe abdominal pain and even vomiting.

Diagnosis of GIST usually requires the help of imaging tests, such as CT or MRI scans, which can help doctors understand the size and location of the tumor. Endoscopy and tissue biopsy are also key steps in confirming the diagnosis. By observing tissue samples under a microscope, doctors can confirm the nature of the tumor.

Treatments for GIST mainly include surgical resection and targeted drug therapy. Surgery is the preferred treatment, especially when the tumor is confined to a certain area. For tumors that cannot be completely removed or have spread, targeted drugs such as imatinib (Gleevec) can effectively control the disease. These drugs work by inhibiting specific molecular pathways to stop the growth of tumor cells.

Regular follow-up and monitoring are essential for patients with GIST. Even after treatment, the tumor may recur, and patients should maintain close communication with their doctors and undergo regular checkups to detect and address any abnormalities in a timely manner. Understanding the characteristics of the disease and treatment options can help patients and their families better cope with this challenge. I hope this information is helpful to you.