What is neurofibromatosis? How is neurofibromatosis treated?

What is neurofibromatosis?

Neurofibromatosis is a benign peripheral nerve disease that is an autosomal dominant genetic disease. Histologically, it originates from the connective tissue of the endoneurial membrane of the peripheral nerve sheath. It often affects organs originating from the ectoderm, such as the nervous system, eyes, and skin, and is one of the common neurocutaneous syndromes.

What to eat for neurofibromatosis?

People with neurofibromatosis should eat more foods such as white fungus, black fungus, shiitake mushroom, hericium erinaceus, chicken gizzard, sea cucumber, coix seed, walnut, crab, skink, and needle fish.

Differential diagnosis of neurofibromatosis

1. Hemangioma

Compressible, red or dark in color.

2. Lymphangioma

Lymphangioma is a common disease of neurofibromatosis. There are small transparent particles protruding on the surface of lymphangioma, and there is no skin melanin deposition.

3. Pigmented spots

It only occurs on the skin, without subcutaneous nodules or subcutaneous tissue hyperplasia.

4. Myxoma

Histopathologically, there are no neural axes or collagen fiber bundles.

5. Myxoid lipoma

Myxoid lipomas have different stages of lipoblasts, nuclear infection, and giant cells. Long spindle cells without corrugated nuclei, no nerve axons, and no collagen fiber bundles.

6. Pork tapeworm

In atypical cases, multiple scattered nodules are found under the skin, which must be differentiated from subcutaneous nodules of Taenia solium metacercariae.

7. Diffuse distribution with larger volume

It needs to be differentiated from cavernous hemangioma, lymphoma, schwannoma, elephantiasis, etc. The surface skin of these lesions is relatively normal, and there is no obvious change in skin color except that cavernous hemangioma may have light blue patches, while the surface skin of neurofibroma often has pigmentation and darkens.