What causes neurofibroma

Neurofibroma may be caused by bad living habits, exposure to harmful substances, genetic factors, diabetes, and high blood pressure. If you experience any discomfort, it is recommended to seek medical attention in a timely manner and receive targeted treatment under the guidance of a doctor. The specific analysis is as follows:

1. Bad living habits: Long-term smoking, drinking, high-salt diet, etc. Harmful substances may directly damage cells and DNA, increase the risk of gene mutation, and promote the occurrence of neurofibroma. Patients should actively change bad living habits, such as quitting smoking, limiting drinking, maintaining a healthy diet and exercise habits, etc. Regular physical examinations and screening for neurofibroma should be performed to detect tumors early and treat them in time.

2. Exposure to harmful substances: Harmful substances may directly or indirectly affect the replication and repair process of DNA, leading to gene mutations and tumors. Harmful substances may also affect the body's immune system, reduce the activity of immune cells, and allow tumor cells to escape immune surveillance and proliferate. Try to avoid contact with known harmful substances, such as certain chemicals, radiation, etc. If you must come into contact with harmful substances, take appropriate personal protective measures, such as wearing protective clothing, masks and gloves.

3. Genetic factors: Neurofibromatosis is a hereditary disease, mainly caused by mutations in the NF1 and NF2 genes. These genes are responsible for encoding proteins that function normally in neurofibroma cells. When these genes mutate, the function of the protein is affected, leading to abnormal cell growth and differentiation, and eventually forming a tumor. For neurofibromatosis that has already occurred, surgical resection is a common treatment method. The surgery should remove the tumor as thoroughly as possible to reduce the risk of recurrence. You can also use drugs for relief under the guidance of a doctor, such as imatinib mesylate tablets, paclitaxel for injection, bevacizumab injection, etc.

4. Diabetes: High blood sugar levels may cause damage to nerve cells, making them more susceptible to gene mutations. Metabolic disorders in diabetic patients may lead to abnormal microenvironment of nerve tissue and promote the occurrence of neurofibromas. It is recommended to adopt a low-sugar, low-fat, high-fiber diet. You can use medications for treatment as prescribed by your doctor, such as glibenclamide tablets, glipizide controlled-release tablets, gliclazide sustained-release tablets, etc.

5. Hypertension: Hypertension leads to increased intravascular pressure, which may damage the blood vessel wall, cause inflammation and fibrosis, which may affect the normal function of nerve sheath cells. Hypertension may affect the metabolism and growth regulation of nerve sheath cells, causing their abnormal proliferation to form fibroids. Reduce sodium intake and maintain a healthy weight. You can use drugs such as amlodipine besylate tablets, nifedipine tablets, and felodipine sustained-release tablets under the guidance of a doctor.

An abnormal immune system may also cause this condition. Pay attention to a healthy diet, adjust your work and rest habits, and exercise appropriately in your daily life to enhance your resistance and avoid the occurrence of uncomfortable symptoms.