What is the order of administration of targeted drugs and chemotherapy drugs for breast cancer

The treatment sequence of breast cancer should be individualized according to the patient's specific situation and the doctor's clinical experience, because each patient's condition and pathological type are different, and the treatment plan will also be different. In some cases, targeted drug treatment is performed first, and then chemotherapy drugs are administered; in some cases, chemotherapy drugs are administered first, and then targeted drug treatment is performed.

1. First, targeted drug treatment, and then chemotherapy: For HER2-positive breast cancer patients, targeted drugs are generally used first, such as trastuzumab or other HER2 inhibitors, which can specifically target HER2-positive breast cancer cells. After targeted therapy, further chemotherapy may be used, such as cisplatin, fluorouracil and other chemotherapy drugs.

2. First administer chemotherapy drugs, then targeted drug therapy: For patients with hormone receptor-positive breast cancer, hormone therapy is generally performed first, such as the use of estrogen receptor modulators or androgen receptor antagonists. After hormone therapy, chemotherapy drugs may be administered, such as cyclophosphamide, doxorubicin and other chemotherapy drugs. If the patient's condition progresses or becomes HER2-positive, targeted drug therapy may be performed after chemotherapy.

The specific treatment sequence needs to be comprehensively judged based on the patient's specific situation, such as the type, stage, genetic mutation, and related concomitant diseases of breast cancer. The doctor's clinical experience and professional opinions are also needed to make decisions. Patients are advised to follow the doctor's instructions.