Is it necessary to do genetic testing after chemotherapy for colon cancer surgery

Generally speaking, whether a colon cancer patient needs genetic testing after surgery depends on the specific situation. If the patient's condition is more serious, genetic testing is generally recommended; but if the condition is mild, it is not necessary.

1. Necessary situations: For some patients with more malignant colon cancer, after radical resection, they still need comprehensive treatments such as adjuvant radiotherapy and chemotherapy to improve the cure rate and quality of life. At this time, it may be necessary to perform genetic testing on tumor cells to understand their mutation types and select corresponding targeted drugs for subsequent individualized precision drug treatment;

2. Unnecessary situations: If the patient is in the early or middle stage of colon cancer and the pathological stage is low, he or she can follow the doctor's advice to use 5-fluorouracil tablets combined with leucovorin capsules and other chemical drugs for systemic intravenous chemotherapy to inhibit the growth and reproduction of residual cancer cells in the body and avoid recurrence and metastasis. In this case, genetic testing is not necessary to avoid increasing the economic burden.

Since different types of cancer have different molecular mechanisms and biological behavior characteristics, more targeted and effective personalized diagnosis and treatment plans should be adopted for different stages of the same disease. It is recommended that patients seek medical treatment in a timely manner, complete examinations and clear diagnosis, and then actively receive standardized treatment.