At present, cervical intraepithelial neoplasia is usually used clinically to reflect the evolution and progression of cervical cancer. Cervical intraepithelial neoplasia includes cervical atypical hyperplasia and cervical carcinoma in situ. Normally, the transformation of normal cervical epithelial cells into cervical intraepithelial neoplasia requires special environmental conditions, such as human papillomavirus infection. It can be said that without human papillomavirus infection, cervical cancer will not occur. However, even if infected with human papillomavirus, cervical cancer does not necessarily occur. Only repeated and continuous human papillomavirus infection is a prerequisite for cervical cancer. Because of repeated and persistent infection, cervical intraepithelial neoplasia may occur. This lesion will go through mild, moderate, severe and then invasive cervical cancer, which takes at least several years or even more than ten years. During this period, the lesion is in a changing state, that is, the lesion will regress, persist and progress. The most common clinical manifestations of cervical cancer Contact bleeding, especially vaginal bleeding after sexual intercourse. In late-stage cases, due to the rupture, necrosis and secondary infection of cancerous tissue, a large amount of purulent or rice-water-like vaginal discharge with a foul odor appears. However, cervical precancerous lesions and cervical intraepithelial neoplasia generally have no obvious symptoms and signs, and nearly half of the cervixes appear normal. Some patients may experience increased vaginal discharge, blood streaked vaginal discharge, contact bleeding, cervical hypertrophy, congestion, erosion, polyps and other manifestations of chronic cervical inflammation. Even if cervical intraepithelial neoplasia develops into cervical carcinoma in situ, half of the patients still have no clinical symptoms. Therefore, it is impossible to diagnose cervical intraepithelial neoplasia and cervical cancer by naked eye observation. At present, clinical diagnosis requires the use of a variety of auxiliary examination methods, such as cervical cytology, human papillomavirus examination, colposcopy combined with cervical biopsy, endocervical curettage and cervical cone excision. It can be seen that there are no obvious symptoms in the early stage of cervical cancer, and the harm of cervical cancer to women is extremely great. It can be said that cervical cancer is an invisible killer around women, so female friends must do a good job of prevention. If adverse symptoms occur, they should go to a regular hospital for treatment as soon as possible to avoid adverse consequences. |
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