Can endometrial cancer, one of the most common gynecological malignancies, be cured?

Endometrial cancer is a relatively common gynecological malignancy. Due to the limitations of medical technology and the complex structure of the uterus, the cause of endometrial cancer is still unclear. So can endometrial cancer be cured in its early stages?

Endometrial cancer is a malignant tumor originating from the endometrial glands, also known as uterine body cancer. It is one of the common gynecological malignancies, prone to menopause and menopause, and is more common in unmarried, underfertile, obese women with hypertension and diabetes. The onset of endometrial cancer is generally believed to be related to estrogen. The most common pathological type is adenocarcinoma. The disease generally develops slowly and is mainly manifested by irregular vaginal bleeding and increased discharge. Various pathways are direct spread or through lymph and blood. The treatment is mainly assisted by surgery for half a year, supplemented by radiotherapy, chemotherapy, progesterone anti-estrogen and other drugs. If it can be discovered early, diagnosed early, and treated correctly early, the effect is better. Recurrence is mostly within 3 to 5 years, and there is a long-term recurrence, so long-term follow-up is required.

Globally, more than 200,000 women die of cervical cancer every year. In developing countries, cervical cancer is a common and frequent gynecological tumor, ranking first. There are 131,500 new cases discovered in my country each year, with the highest mortality rate in Shanxi and the lowest in Tibet. Cervical cancer refers to malignant tumors that occur in the vaginal part of the uterus and the cervical canal. The general trend is that rural areas are higher than urban areas and mountainous areas are higher than plains. According to retrospective surveys of provinces, cities and autonomous regions, the mortality rate of cervical cancer in my country ranks 10th among all cancer mortality rates and 10th among female cancers. The metastasis of cervical cancer can spread directly to adjacent tissues and organs, downward to the vaginal vault and vaginal wall, upward to invade the uterine body, to the sides to invade the pelvic tissue, forward to invade the bladder, and backward to invade the rectum. It can also metastasize to the paracervical, internal iliac, external iliac, and inguinal lymph nodes through lymphatic vessels, and even metastasize to the supraclavicular and other lymph nodes throughout the body in the late stage. Hematogenous metastasis is relatively rare, and common metastatic sites are the lungs, liver and bones. When the symptoms of cervical cancer appear three months later, 2/3 of the patients have advanced cancer.

Can early-stage endometrial cancer be cured? This question is closely related to the patient's own situation and the choice of treatment. Surgery is the first choice for uterine cancer that has not metastasized or spread. The first choice for early-stage endometrial cancer is total hysterectomy, including removal of the uterus, cervix, ovaries, and fallopian tubes. Extensive surgery is sufficient to cure early-stage uterine cancer and prevent recurrence as much as possible. If the cancer has spread beyond the uterus, radiotherapy is supplemented after surgery to eliminate residual cancer cells. When the cancer has not spread and the lesion is large, some doctors also recommend radiotherapy.