The normal value of EGF (epidermal growth factor) is used as a reference value for diagnosing various tumors and ulcer diseases. The reference range of normal EGF values is: serum: 1032±485pg/ml; plasma: 192±106pg/ml. Increased: Abnormal expression of EGF and its receptors is found in many tumors, and is closely related to tumor metastasis and patient prognosis, such as gastric cancer and liver cancer. In gastric cancer patients, the lower the degree of differentiation of gastric cancer cells, the higher the EGF level; the serum EGF level of patients with advanced gastric cancer is higher than that of patients with early stage. EGF and its receptors are also significantly increased in liver cancer tissue and precancerous lesion tissue. Reduction: EGF has a wide range of biological effects on the digestive system. It can stimulate target cell DNA synthesis, regulate cell defense and gastrointestinal secretion, act on parietal cells, and inhibit gastric acid and pepsin secretion. Therefore, EGF may be a natural growth factor of the gastrointestinal mucosa and is related to the occurrence of peptic ulcers. The EGF content in the gastric juice and serum of patients with duodenal ulcers is significantly reduced. In addition, there are some things to note about the egf check: 1. The patient needs to be fasting on the day of the examination; 2. Relax when drawing blood to avoid vasoconstriction due to fear, which may increase the difficulty of blood collection; 3. After the blood test, apply local pressure on the needle hole for 3 to 5 minutes to stop the bleeding. Be careful not to rub it to avoid causing subcutaneous hematoma. |
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