Is sex cord-stromal cell tumor cancer? Four types of sex cord-stromal cell tumors may become cancerous

Sex cord stromal tumor is a potential malignant tumor that occurs on the ovary. It has a very high recurrence rate and is composed of ovarian granulosa cells, theca cells, supporting cells, Leydig cells and fibroblasts alone or in combination. It is extremely harmful to patients. So, is sex cord stromal tumor a cancer?

Sex cord-stromal tumors are a type of tumor that arises in the interstitial part of the ovary or testis and contains granulosa cells, theca cells, and fibroblasts. This disease accounts for 8% of ovarian cancers and less than 5% of testicular cancers. The accurate diagnosis of this tumor can only be based on biopsy, and it is often a malignant tumor. Solid ovarian tumors are common in postmenopausal women. For men, this type of tumor is very rare, far less than testicular germ cell tumors; for women, it is also slightly less than ovarian germ cell tumors.

1. Granular-stromal cell tumors include a group of ovarian sex cord-stromal tumors composed of granules, theca or cells similar to stromal fibroblasts. Granular cell tumors are divided into adult and juvenile types; theca-fibroblast group is classified into theca cell tumor, fibroma, fibrosarcoma, stromal tumor with a small amount of sex cord components, sclerosing stromal tumor and signet ring stromal tumor.

2. Sertoli-stromal cell tumors are a group of testicular sex cord-stromal tumors composed of supporting cells, testicular reticulum epithelium, fibroblasts, and Leydig cells alone or in combination, including supporting-Leydig cell tumors, supporting cell tumors, and stromal and Leydig cell tumors.

3. Sex Cord-stromal tumors of mixed or unclassified cell types refer to sex cord-stromal tumors other than granulosa-stromal, supporting stroma and steroid cells, including annular sex cord tumors, gynecoma and nonspecific cord-stromal tumors.

4. Steroid cell tumors: This is a group of tumors of unclear origin, composed of cells similar to those that secrete steroid hormones, and was previously called "lipid cell tumors". This group of tumors mainly includes nonspecific steroid cell tumors, interstitial lutein tumors, and Leydig cell tumors.