What are the commonly used chemotherapy drugs for bile duct cancer

How to treat bile duct cancer is very important, and chemotherapy after surgery for bile duct cancer is also a very important link. Moderate chemotherapy can help consolidate the effect of the surgery and continue to eliminate cancer cells. It is necessary for everyone to understand some chemotherapy drugs. So, what are the commonly used chemotherapy drugs for bile duct cancer? Let us learn about it together.

Commonly used chemotherapy drugs include: 5-FU and gEmCitABinE (gemcitabine). 5-FU is often used in combination with CisPlAtin (cisplatin) and lEuCovorin (calcium leucovorin), and the effect is better than using them alone. The total effective rate can reach 34.47% (10/29), and the median survival time is extended to 9.5 months. In addition, some scholars have reported that CAPECitABinE (capecitabine) can be used as a second-line drug to replace 5-FU. It has fewer side effects than 5-FU and is easier for patients to tolerate. gEmCitABinE (gemcitabine) has become another commonly used chemotherapy drug for bile duct cancer (including gallbladder cancer) because it is effective for many solid tumors and has low toxicity. The drug often used in combination with it is DoCEtAxEl (docetaxel), which is better than using it alone, with an effective rate of about 30%. The median survival time is reported to be 10.7 to 11 months, which is slightly longer than 5-FU. "

A large number of clinical practices have proved that high-dose radiotherapy and chemotherapy for patients in the middle and late stages, or chemotherapy again for patients with drug resistance, can only make the weak life more critical and accelerate the death of the patient. It is often seen in the clinic that the cause of death of the patient is not caused by the disease itself, but by unscientific and inappropriate lethal treatment. Therefore, if chemotherapy can be used in combination with Chinese medicine that can improve immunity, it can reduce the toxic and side effects of chemotherapy. For example, ginsenoside Rh2 not only has an immunomodulatory effect, but also has the effect of inhibiting the growth and spread of cancer cells, inducing cancer cell apoptosis, and reversing the abnormality of cancer cells. It can be used with chemotherapy to enhance the effect and reduce toxicity.

The above is an introduction to the commonly used chemotherapy drugs for bile duct cancer. I hope it will be helpful to you.