What are the treatments for osteosarcoma

As medical technology becomes more and more advanced, more and more effective methods for treating osteosarcoma have emerged, which brings good news to osteosarcoma patients. We always believe that as long as osteosarcoma adheres to symptomatic treatment, it will soon be possible to restore a healthy body. Let's take a look at the treatment methods for osteosarcoma.

The treatment of osteosarcoma is a comprehensive treatment with surgery as the main method, that is, chemotherapy before surgery and chemotherapy after surgery. A considerable number of cases (about 66%) have satisfactory chemotherapy effects. Chemotherapy greatly improves the survival rate by inhibiting the occurrence of lung metastasis, and chemotherapy greatly increases the chance of limb-saving surgery without the need for amputation. For typical osteosarcoma, if the preoperative chemotherapy is effective, extensive large-block resection can be performed. However, if chemotherapy is ineffective, radical resection or amputation should be performed. Lung metastases can often be treated with resection.

1. Chemotherapy

Chemotherapy is an important adjuvant treatment for osteosarcoma. High-dose chemotherapy combined with multiple drugs can kill the tumor locally. Preoperative chemotherapy (neoadjuvant chemotherapy) can cause tumor cell necrosis, tumor shrinkage, disappearance of edema and new tumor blood vessels in the reaction area, and clearer boundaries of tumor calcification. Clinically, the patient's pain is reduced or disappears, the tumor becomes smaller, the joint range of motion increases, and AKP can be reduced to normal.

High-dose chemotherapy is also an effective systemic treatment for osteosarcoma. Chemotherapy can kill micro-metastases in the lungs and throughout the body. This treatment should be performed early. Micro-lesions are more sensitive to chemotherapy than large tumors. Adjuvant chemotherapy can reduce the number of tumors in the lungs and delay their appearance. The key to prolonging the survival of patients with lung metastases is to completely remove the metastases. Chemotherapy can promote the radical cure of the entire disease and increase the cure rate.

2. Amputation

For patients who seek medical treatment late and are unable to undergo chemotherapy, amputation is still the best treatment method to relieve pain and prolong survival. Usually, a shorter course of chemotherapy should be done before surgery, and chemotherapy should be continued 2 weeks after surgery.

3. Syndrome differentiation and treatment of osteosarcoma, TCM treatment of osteosarcoma

Prescription: ① Codonopsis pilosula 9g, Astragalus membranaceus 9g, Radix Angelicae Sinensis 9g, Radix Paeoniae Rubra 9g, Atractylodes macrocephala 9g, Radix Chuanduan 12.5g, Radix Evodiae 31g, Vaccariae Semen 9g, Oyster 31g, Herba Prunellae 12.5g, Pericarpium Citri Reticulatae 6g, Radix Aucklandiae 5g, Seaweed and Kelp 12.5g each (decoction). At the same time, take Erhuang Pills (5 li), 1 pill per week.

Efficacy: Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine reported a case of osteolytic sarcoma that was cured.

②Oral prescription: 9g each of Corydalis, frankincense, myrrh, Danshen, safflower, Liuji Nu, Achyranthes bidentata, Dipsacus asper, Leonurus japonicus, 6g each of Sappanwood and Sanguisorba officinalis, 3g of Eupolyphaga sinensis, decocted in water. External application: 12.5g of Angelica sinensis, 9g each of Paeonia lactiflora, Catechu, Realgar, Liuji Nu, Sanguisorba officinalis, 6g each of frankincense and myrrh, 2g of Crocus saffron, 3g of Borneol, 0.15g of Musk. Grind into powder and apply to the affected area, change it every 3 days, remove it, add a little new medicine and apply it again.

Efficacy: Hunan Institute of Traditional Chinese Medicine reported a case of giant cell tumor of bone that was cured.

Folk remedy: 30 grams of coix seed, 30 grams of mung bean, and 30 grams of red bean. Cook them like porridge and eat the beans and drink the soup.

In short, the best cure for osteosarcoma in the early stages is amputation. Therefore, once symptoms of osteosarcoma are discovered, timely examination should be carried out, and amputation or chemotherapy should be performed in a timely manner if the diagnosis is confirmed.