Causes of endometrial cancer

I believe that many friends have heard of the disease of endometrial cancer, but they don’t know much about the related risk factors of endometrial cancer. What are the reasons that make more female friends suffer from endometrial cancer? Why do more patients suffer? The following article will introduce to you in detail the causes of endometrial cancer so that you can better stay away from these risk factors.

The first cause of endometrial cancer is hypertension. Many patients with endometrial cancer are accompanied by hypertension. Obesity, diabetes and hypertension coexist in patients with endometrial cancer, which is called the "endometrial triad" or "endometrial cancer syndrome". The three may be related to a high-fat diet, which is directly related to endometrial cancer. Endometrial cancer is one of the three most common malignant tumors of the female reproductive system in my country. Is there any convenient and easy way to prevent it? A special survey recently reported that drinking tea, especially green tea, may have a certain preventive effect on endometrial cancer, but this preventive effect may only be limited to premenopausal women.

The researchers took all new cases of endometrial cancer diagnosed between January 1997 and December 2002, aged 30 to 69 years old, with permanent residence in Shanghai as the research subjects, and randomly selected healthy women of corresponding age groups from the entire population of Shanghai city as controls.

The survey results show that tea drinkers, especially green tea drinkers, have a lower risk of endometrial cancer than non-drinkers. And the more times you drink tea, the more significantly your risk of endometrial cancer is reduced. For those who drink tea 7 times or more per week, their risk of endometrial cancer is reduced by about 20%. For green tea drinkers who have no history of drinking or smoking, their risk of endometrial cancer is reduced by about 23%. Among them, those who drink more than 200 grams of green tea per month have a risk of endometrial cancer reduced by about 30%.

Researchers pointed out that endometrial cancer is a hormone-dependent tumor, and excessive estrogen exposure is its main cause. Green tea may reduce the risk of endometrial cancer by reducing estrogen levels in the body. In addition, tea polyphenols can enhance lymphocyte proliferation and enhance the body's immune function. Since there are no other reports on tea drinking and endometrial cancer, further epidemiological studies, especially cohort studies, are expected to confirm this.

The second cause of endometrial cancer is early menarche and late menopause. The incidence of endometrial cancer is 60% higher in women who have their menarche before the age of 12 than in those who have their menarche after the age of 12. The absolute age of endometrial cancer is 6 years later than that of normal women.

The third cause of endometrial cancer is exogenous estrogen. Women who take estrogen have a high risk of developing endometrial cancer. The risk is related to the dose, duration of use, whether progesterone is used in combination, whether the drug is stopped in the middle, and patient characteristics. The risk decreases after stopping the drug, but the risk continues for a few years. At present, there is sufficient evidence for the causal relationship between estrogen and endometrial cancer.

The fourth cause of endometrial cancer is obesity. Excessive fat will increase the storage of estrogen and increase the conversion of androstenedione in plasma to estrone. This increase in free and active estrone may be a carcinogenic factor or a cancer-promoting factor for endometrial cancer.

The fifth cause of endometrial cancer is menstrual disorders. The incidence of menstrual disorders and heavy menstruation in patients with endometrial cancer is three times higher than that in normal women.

The above article introduces the causes of endometrial cancer. I hope everyone can understand that endometrial cancer threatens women's health and our happy family. Therefore, we must actively treat this disease, take good care of ourselves in daily life, develop a more regular diet, and learn to relieve stress.