Hematogenous metastasis of endometrial cancer is common in the late stage

What are the common ways of metastasis in late-stage endometrial cancer? Endometrial cancer metastasis refers to the spread of cancer cells to other parts of the body through various pathways, forming cancerous tissue. Endometrial cancer metastasis not only increases the difficulty of cancer treatment, but also increases the pain of patients. Therefore, we should understand the metastasis pathways and symptoms of endometrial cancer, and take timely prevention and treatment measures.

So, what are the common ways of metastasis of late-stage endometrial cancer? Please let the experts give us a brief introduction.

Common metastatic pathways in advanced endometrial cancer

1. Lymphatic metastasis:

Lymphatic metastasis is the main metastatic pathway for endometrial cancer. When the tumor infiltrates into the deep muscle layer or spreads to the cervical canal, or when the cancer tissue is poorly differentiated, lymphatic metastasis is likely to occur. The lymphatic metastasis pathways of cancer lesions in the lower uterine segment and cervical canal are the same as those of cervical cancer, and can reach the parauterine internal iliac, external iliac, and common iliac lymph nodes. Cancer lesions on the posterior wall of the uterus can spread along the uterosacral ligament to the rectal lymph nodes; cancer lesions on the anterior wall can spread to the bladder lymph nodes. Endometrial cancer can also drain retrogradely to the anterior wall of the vagina via lymphatic vessels.

2. Direct spread:

The most common cause in clinical practice is the spread of inflammation in the endometrium, which can extend upward through the uterine horn to the fallopian tube, downward to the cervical canal, and continue to spread to the vagina. It can even extend to the fallopian tube and ovary, and flow to the pelvic peritoneum, uterine rectal pouch and greater omentum.

3. Hematogenous metastasis:

In the late stage, it can be transferred to various tissues throughout the body through the blood, and the common sites are the lungs, liver, bones, etc. Compared with the characteristics of blood transmission, the main symptom of endometrial cancer is abnormal uterine bleeding, and about 90% of patients will have such symptoms. Therefore, in the infection stage of endometrial cancer, this period is also the easiest stage for detection.

Warm reminder: The above content is a brief introduction by experts on "What are the common metastatic modes of late endometrial cancer?" I hope it can be helpful to you. Experts believe that it is unfounded to call cancer a terminal illness. The World Health Organization has clearly stipulated that cancer should be included in the ranks of chronic diseases. Cancer patients should seek the cause through syndrome differentiation and treat the cause based on the diagnosis. As long as the syndrome differentiation is accurate and the medication is appropriate, it is possible to survive with the tumor.