Endocrine and molecular targeted therapy for breast cancer

Endocrine and molecular targeted therapy for breast cancer

Breast cancer patients should choose appropriate treatment methods according to their own conditions. Endocrine and molecular targeted treatment methods are available to patients.

Endocrine therapy

The main endocrine therapies for breast cancer include estrogen antagonists (tamoxifen) and aromatase inhibitors (third-generation aromatase inhibitors, such as letrozole, anastrozole, and exemestane, are commonly used now). Tamoxifen can be used by both pre- and post-menopausal women, and aromatase inhibitors are more effective for post-menopausal women. In addition, there are castration drugs (such as Zoladex) that can replace surgery and radiotherapy, which can be used in pre-menopausal (including peri-menopausal) patients or in combination with tamoxifen and aromatase inhibitors.

Molecular targeted therapy

Humans can develop new drugs targeting different targets at the molecular level. Targeted drugs for the treatment of breast cancer are drugs targeting the HER-2 receptor family (trastuzumab/Herceptin, lapatinib), angiogenesis inhibitors (bevacizumab/Avastin) have been used clinically, and drugs targeting other targets such as the RAS family, farnesyl transferase inhibitors, and ubiquitin-protease pathways. Trastuzumab is the first molecular targeted drug in the field of breast cancer treatment, and its indication is HER-2 positive patients.

Tips: HER-2 positive means that the HER-2 expression is rated as +++ by immunohistochemistry, or positive by FISH test.

<<:  What is the most beneficial diet in the 4 stages after esophageal cancer surgery

>>:  Commonly used auxiliary examination methods for diagnosing breast cancer

Recommend

What are the causes of lymphoma and how to prevent it in life

What are the causes of lymphoma? How can we preve...

Sports Sunglasses

Sports sunglasses are mainly a common type of sun...

How to check for early endometrial cancer

Endometrial cancer may be unfamiliar to many wome...

What is the cause of bleeding from the mouth and nose

When we watch TV, especially ancient martial arts...

Is liver ascites in the late stage?

We all know that the liver is a very important or...

How long can you live with stage 4 lymphoma

This is the issue that many patients and their fa...

What are the symptoms of hypoglycemic encephalopathy?

Hypoglycemic encephalopathy is mainly caused by d...

What are the benefits of eating sesame for children

The physical health of children is the most impor...

Can a mole be removed casually?

Everyone has moles to some extent. If the mole is...

Urine specific gravity is high

Urine is the excess water excreted by the human b...

Sharp and wet scrotum

Many men will feel scrotal pain. A careful observ...

My nose is filled with water and my head hurts

People's five senses are connected to the bra...

Calories of a winter date

Winter dates are a type of dates harvested in aut...

What should patients eat before pituitary tumor surgery

Pituitary tumor is a tumor disease that is very h...