Obese menopausal women are more susceptible to ovarian cancer

Obese menopausal women are more susceptible to ovarian cancer

Ovarian cancer is a common tumor of the female reproductive system. It is highly malignant and has a poor prognosis. The 5-year survival rate is less than 40%, which seriously endangers women's health and life. The latest research finds that obesity can increase the risk of ovarian cancer in postmenopausal women by affecting hormone secretion in their bodies.

After analysis, the researchers found that among women who did not use hormone replacement therapy after menopause, obese women had an 80% higher risk of ovarian cancer than women with normal weight; among women who used hormone replacement therapy after menopause, there was no significant difference in the risk of ovarian cancer between obese women and those with normal weight; women who used hormone replacement therapy had a lower risk of ovarian cancer than those who did not use replacement therapy.

Michael Leitzman and others from the National Cancer Institute of the United States conducted a seven-year follow-up survey on 94,525 American women aged 50 to 71 and found that obese postmenopausal women continue to produce estrogen in their bodies, further promoting the growth of ovarian cells, thereby increasing the risk of ovarian cancer. Hormone replacement therapy refers to a treatment method that treats diseases caused by hormone imbalance by supplementing hormones. It helps menopausal women maintain normal hormone levels in their bodies.

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