Systemic symptoms of patients with lymphoma

The clinical manifestations of lymphoma mainly include fever, skin itching, alcohol pain, etc.

1. Fever

At the beginning, some patients mainly have low-grade fever in the afternoon, and the body temperature returns to normal levels after midnight. Later, as the disease progresses, the patient will show remittent fever, generally starting to have a fever in the afternoon and approaching normal levels by the next morning. Patients in the late stage may show intermittent fever and maintain a cyclical state.

2. Itchy skin

Skin itching is a relatively specific manifestation of lymphoma, and generally 85% of patients may experience this symptom. Skin scratches are common on the trunk and limbs, and focal itching may also occur in the area of ​​lymphatic drainage of the lesion.

3. Alcohol Pain

About 1.6% to 5.3% of patients will experience pain in the swollen lymph nodes after drinking alcohol, which is more common in women, mediastinal lesions and nodular sclerosis of Hodgkin's lymphoma (HL). Due to the characteristics of this symptom, it can appear earlier than other symptoms and X-ray manifestations, so it has certain diagnostic significance. In addition, alcohol pain disappears after the lesion is relieved, and alcohol pain reappears after the lesion relapses.