What are the symptoms of lymphoma in the middle and late stages?

Due to the different locations and ranges of the lesions, the symptoms of lymphoma in the middle and late stages vary greatly. Primary lesions can be found in lymph nodes or in organs other than lymph nodes. So what are the specific symptoms of lymphoma in the middle and late stages? Today we will give you a detailed introduction:

1. Fever: Fever patterns are mostly irregular, and can be continuous high fever, or intermittent low fever. A few have periodic fever, the latter of which is seen in about 1/6 of Hodgkin's disease patients. Early fever accounts for about 30% to 50% of Hodgkin's disease, but non-Hodgkin's lymphoma generally only causes fever when the lesions are more extensive. Profuse sweating when the fever subsides can be a characteristic of this disease.

2. Skin itching: This is a more specific manifestation of Hodgkin's disease. Focal itching occurs in the area of ​​lymphatic drainage of the lesion, and systemic itching mostly occurs in cases with lesions in the mediastinum or abdomen.

3. Alcohol pain: About 17% to 20% of patients experience pain in the lesion 20 minutes after drinking. The symptoms may appear earlier than other symptoms and X-ray manifestations, and have a certain diagnostic significance. When the lesion is relieved, the alcohol pain disappears immediately, and it worsens when it recurs.

4. Symptoms of extranodal lesions:

1) Gastrointestinal tract: Lymphoma lesions in extranodal lymphoid tissue are most common in the gastrointestinal tract, accounting for 13% to 25% of non-Hodgkin's lymphoma and only 2% of Hodgkin's disease. Clinical manifestations include loss of appetite, abdominal pain, diarrhea, abdominal distension, intestinal obstruction and bleeding. The most common site of invasion is the small intestine, of which more than half are the ileum, followed by the stomach. The colon is rarely affected. Primary small intestinal tumors are most common in non-Hodgkin's lymphoma, with malabsorption syndrome or steatorrhea as the main clinical manifestations, and lesions often occur in the jejunum. Gastrointestinal lesions generally spread from the retroperitoneal lymph nodes through the mesenteric lymphatic vessels.

2) Hepatobiliary: Invasion of the liver parenchyma may cause pain in the liver area. Jaundice may occur when diffuse infiltration or enlarged lymph nodes in the liver are detected by the common bile duct. About 15% of patients with Hodgkin's disease involving the liver have jaundice.

3) Skeleton: Clinical manifestations include local bone pain and secondary nerve compression detection symptoms.

4) Skin: Nonspecific lesions commonly include pruritus and prurigo. Pruritus is more common in Hodgkin's disease (accounting for 85%) and may appear before other rashes. Severe sweat retention can also be seen occasionally.

5) Tonsillar and oral, nasal, and pharyngeal lymphomas that invade the oral and nasopharyngeal regions may present clinical symptoms such as dysphagia, nasal congestion, and epistaxis.

6) Others: Lymphoma can also infiltrate the pancreas and cause malabsorption syndrome. Mediastinal lymphoma can metastasize to the pericardium and cause local tumors. Infiltration of the breast, thyroid, lacrimal gland, bladder, testicles, and ovaries, which can cause corresponding symptoms, is very rare.

The systemic symptoms of malignant lymphoma vary greatly depending on the type of disease and the stage of the disease. Some patients may have no systemic symptoms. Those with symptoms may have fever, weight loss (

The above is an introduction to the specific symptoms of lymphoma in the middle and late stages. I believe you must have understood it and hope it can be helpful to you. If you have other questions, please consult our online experts, who will give you detailed answers. Feihua Health Network wishes you good health!

Lymphoma http://www..com.cn/zhongliu/lb/