What are the common symptoms of pancreatic cancer?

The clinical symptoms of pancreatic cancer mainly depend on the location of the tumor, whether the surrounding organs are affected, and whether complications occur. Generally speaking, pancreatic head cancer often shows symptoms relatively early, while body and tail cancer have few early symptoms. Below, please ask the hospital experts to introduce you in detail;

(1) Abdominal pain is the most common symptom of pancreatic cancer. It is the first symptom in more than 60% of patients. The location of abdominal pain in pancreatic cancer is deeper and the location is not very precise. It is most common in the upper abdomen. According to the location of the tumor, abdominal pain in pancreatic head cancer is mostly in the right upper abdomen, while that in pancreatic tail cancer is in the left upper abdomen. In the early stage, due to incomplete obstruction of the common bile duct or pancreatic duct, bile is not drained smoothly after meals, so patients often feel discomfort and dull pain in the upper abdomen. When the obstruction is complete, the upper abdomen is dull and worse after meals. Patients in the middle and late stages often have low back pain, which is related to body position. It is aggravated when lying on the back and relieved when bending forward or lying on the side. Patients often dare not lie down at night and lie prone or sit forward.

(2) Jaundice is mainly seen in cases of pancreatic head cancer. Although jaundice can be the first symptom of pancreatic cancer, it is not an early manifestation. In the past, it was emphasized that the characteristic of pancreatic cancer jaundice is progressive and aggravated painless jaundice. However, recent observations have found that the jaundice of some patients may fluctuate. When the tumor is combined with inflammation, it can be temporarily relieved after anti-inflammatory or hormone treatment. At the same time, most patients have varying degrees of abdominal pain, and only about 25% of patients have painless jaundice.

(3) Hepatomegaly: About 50% of patients may have hepatomegaly, mainly due to cholestasis, occasionally due to portal hypertension or cancer metastasis.

(4) Gallbladder enlargement When pancreatic cancer causes extrahepatic obstructive jaundice, an enlarged gallbladder can sometimes be palpated. According to Courvoisier's rule (painless jaundice - gallbladder enlargement), it is important to make a differential diagnosis from cholelithiasis. However, in fact, less than half of patients with pancreatic cancer and jaundice can palpate an enlarged gallbladder, which may be related to the fact that the enlarged liver covers the enlarged gallbladder and the small size of the gallbladder in chronic cholecystitis.

(5) Weight loss is a common symptom of pancreatic cancer patients (65% to 90%). The characteristic of weight loss in pancreatic cancer patients is that it develops rapidly.

(6) Abdominal masses The pancreas is located deep in the body, and pancreatic cancer patients generally cannot easily palpate abdominal masses. Once a mass is palpated,

Tumors grow by absorbing nutrients from the host through blood vessels to supply their own growth. Once this supply is lost, the tumor will produce some new blood vessels to connect with the large blood vessels to supply nutrients for tumor growth. This phenomenon is called compensatory tumor angiogenesis.

Therefore, angiogenesis is closely related to tumor generation, growth, infiltration and metastasis, and also provides a new way for people to treat tumors. This also breaks the difficult situation of cancer treatment, and cancer patients see the dawn of new life again. If you have other relevant information about pancreatic cancer, please click to consult our online experts and we will give you a detailed introduction;

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