Pain in the front thigh muscles

People will occasionally feel pain in the muscles in the front of their thighs. This situation is quite common. The most important thing at this time is to prescribe the right medicine, so as to prevent various infections. Some patients may also need systemic treatment. After all, muscle pain can lead to very serious diseases, which will bring quite a lot of sequelae to the patient's body.

1. Use adrenocortical hormones or immunosuppressants as soon as possible;

2. Symptomatic and supportive treatment to prevent and treat various infections;

3. Plasma exchange therapy;

4. High-dose immunoglobulin therapy;

5. Whole body radiotherapy for stubborn and severe cases.

Medication principles:

1. Adrenal cortical hormones (dexamethasone, prednisone), hydrocortisone, methylprednisolone (methylprednisolone)), etc. are effective for most polymyositis and are the first choice for treating this disease. It is generally recommended to use high-dose shock in the early stage and medium-dose consolidation treatment for no less than 3 months, and low-dose maintenance time should not be shorter than 2 years.

2. For patients with ulcer disease, hypertension and diabetes who cannot use corticosteroids, as well as those whose muscle weakness and myalgia have not improved after 3 months of regular hormone treatment, immunosuppressants (cyclophosphamide, azathioprine or methotrexate) should be used instead or added. This is especially suitable for those with malignant tumors.

3. Large doses of immunoglobulin and plasma exchange therapy have a therapeutic effect on this disease, but require higher medical costs.

4. When using large amounts of hormones, immunosuppressants, etc. for a long time, attention should be paid to the side effects of the drugs, and symptomatic and supportive treatment should be strengthened. For those with concurrent infections, sufficient and effective antibiotics should be used as early as possible.

1. Apply corticosteroids. Take 40-60 mg/d of prednisone at once. After the condition stabilizes, the dosage can be gradually reduced. For critically ill patients, hydrocortisone 200-300 mg/d, or dexamethasone 10-20 mg/d added to 10% glucose for intravenous drip. After the condition stabilizes, switch to oral administration and adjust the dosage to the level with the best therapeutic effect and the least side effects as the maintenance dose, sometimes for 2-3 years. ACTH should be used intermittently during the treatment.

2. Patients who do not respond to short-term high-dose hormone treatment should consider stopping the medication and switch to immunosuppressants, such as azathioprine 100-200 mg per day. Watch out for side effects. Nandrolone phenylpropionate 25 mg intramuscular injection twice a week is effective in relieving pain and symptoms.

3. Those who have difficulty swallowing should be fed through nasogastric feeding to ensure adequate nutrition. Patients with airway obstruction or respiratory muscle paralysis require timely tracheotomy and assisted breathing. Qianglining has hormone-like effects without the side effects and can be used. 40mgV.D once/d.

4. Plasma exchange therapy can be performed if conditions permit.