Will I be allergic to roxithromycin?

In daily life, any medicine can cause allergies, but erythromycin rarely causes allergies. However, the possibility of allergies cannot be ruled out. Everyone's physical fitness is different. If allergic symptoms such as erythema appear on the body after taking the medicine, you must stop using the medicine immediately and go to the hospital for anti-allergic treatment in time. Don't be careless and must take it seriously. If the allergy is serious, timely medical treatment is very critical.

Symptoms of allergy to roxithromycin

Roxithromycin is suitable for pharyngitis and tonsillitis caused by Streptococcus pyogenes, sinusitis, otitis media, acute bronchitis, acute exacerbation of chronic bronchitis caused by sensitive bacteria, pneumonia caused by Mycoplasma pneumoniae or Chlamydia pneumoniae; urethritis and cervicitis caused by Chlamydia trachomatis; skin and soft tissue infections caused by sensitive bacteria.

There are many types of allergies, in various shapes and colors. One of the most common drug rashes is dark red papules, which look very similar to the rash that children get when they have measles, and is called "measles-like drug rash."

What to do if you are allergic to roxithromycin

First, you should make sure that you are allergic to roxithromycin and have not consumed any other foods that may cause allergies. You should stop taking the medication immediately. If the situation is serious, you should consult a doctor immediately. When using medication in the future, use other types of antibiotics.

Pharmacology and Toxicology of Roxithromycin

Roxithromycin is a semisynthetic 14-membered ring macrolide antibiotic. The antibacterial spectrum and antibacterial effect are basically similar to those of erythromycin. Its effect on Gram-positive bacteria is slightly weaker than that of erythromycin, but its effect on Legionella pneumophila is stronger than that of erythromycin. Its antimicrobial effect against Chlamydia pneumoniae, Mycoplasma pneumoniae, and Ureaplasma urealyticum is similar to or slightly stronger than that of erythromycin.

This product can penetrate the bacterial cell membrane and reversibly bind to the 50S subunit of the bacterial ribosome near the donor ("P" position), blocking the transfer RNA (t-RNA) binding to the "P" position, and also blocking the transfer of the polypeptide chain from the acceptor position ("A" position) to the "P" position, thereby inhibiting bacterial protein synthesis.

The antibacterial spectrum of roxithromycin tablets is similar to that of erythromycin. Roxithromycin tablets are highly sensitive or relatively sensitive to Staphylococcus aureus (except MRsA), Streptococci (including Streptococcus pneumoniae and type A, B, and C streptococci, but excluding type G and enterococci), Corynebacterium, Listeria, Moraxella catarrhalis (Catarrhea), Legionella, etc. Roxithromycin tablets also have good antibacterial effects on anaerobic bacteria such as oral Bacteroides, black-producing Bacteroides, Peptococcus, Peptococcus, Propionibacterium acnes, as well as Toxoplasma gondii, Chlamydia, and Treponema pallidum. Roxithromycin tablets have weaker effects on Helicobacter, gonococci, meningococci, and Bordetella pertussis.

The activity of roxithromycin tablets against Gram-positive bacteria is slightly worse or similar to that of erythromycin. The activity of roxithromycin tablets against Haemophilus influenzae and Moraxella catarrhalis is weaker than that of erythromycin, with MIC90 being higher than 13 mg/L and 0.89 mg/L, respectively. Roxithromycin tablets are more sensitive to gonococci and Legionella pneumophila than erythromycin, with MIC90 of about 0.25 mg/L. The effect of roxithromycin tablets on anaerobic bacteria is similar to that of erythromycin, with a MIC90 of 24 mg/L for Bacteroides. The effect of roxithromycin tablets on Clostridium is slightly stronger than that of erythromycin, with a MIC90 of 3.3 mg/L. Chlamydia pneumoniae (MIC900.25mg/L), Mycoplasma pneumoniae (MIC900.03mg/L), and Ureaplasma urealyticum (MIC901mg/L) are sensitive to this product, and its effects are mostly stronger than erythromycin.

Roxithromycin tablets are used to treat infections caused by roxithromycin-susceptible pathogens. Roxithromycin tablets are used to treat ear, nose and throat infections: tonsillitis, pharyngitis, sinusitis; Roxithromycin tablets are used to treat respiratory tract infections: acute bronchitis, pneumonia; skin and soft tissue infections: impetigo; urogenital tract infections: non-gonococcal urethritis.

Allergic reactions to roxithromycin tablets: Occasionally (≥0.1%-<1%), treatment with roxithromycin can result in allergic reactions of varying severity. These allergic reactions are mostly skin and mucous membrane reactions, such as redness, swelling with or without itching or purpura, and more rarely swelling of the face, tongue and/or throat, as well as difficulty breathing and even possible fatal shock. In these cases, roxithromycin should be discontinued immediately; in some cases, appropriate treatment (e.g., electroconvulsive therapy) should be initiated promptly.