If my mother has polycystic kidney disease, will it be inherited?

Many people are familiar with polycystic kidney disease, which is a hereditary disease. Polycystic kidney disease is a hereditary disease caused by many cysts in the cortex and medulla of the kidney. Many people are very concerned about whether this disease is hereditary and want to know whether polycystic kidney disease will be 100% inherited to the next generation. So, will my mother's polycystic kidney disease be inherited?

First, if the mother has polycystic kidney disease, will it be inherited? The inheritance of polycystic kidney disease can be divided into two types: adult polycystic kidney disease is chromosomal dominant inheritance, and infantile polycystic kidney disease is chromosomal recessive inheritance. Nephrology experts said that polycystic kidney disease is not only affected by genetic factors, but also has a certain relationship with the patient's age and region. According to the inheritance pattern, it can be divided into autosomal dominant polycystic kidney disease and autosomal recessive polycystic kidney disease. Let’s take a look at the inheritance of polycystic kidney disease. The genetic incidence of adult polycystic kidney disease is about 0.2%, which is mainly characterized by the occurrence, development and increase in the number of kidney cysts, often accompanied by the formation of cysts in other organs, most commonly in the liver, but can also be seen in the pancreas, ovaries, and gastrointestinal tract.

Second, the inheritance rule of autosomal recessive polycystic kidney disease is: if both parents are heterozygous, their homozygous offspring will develop the disease, and the probability of developing the disease is 25%. No gender or race distinction. Congenital dysplasia: Congenital dysplasia can cause a variety of diseases. For cystic kidney disease, it can mainly cause medullary sponge kidney, dysplastic polycystic kidney disease, etc. The genes of congenital dysplasia are generally not abnormal, so it is different from genetic inheritance or gene mutation.

If the mother has polycystic kidney disease, will it be inherited? Various infections: Infections can cause abnormal changes in the body's internal environment, thereby creating environmental conditions that are conducive to changes in cyst genes, enhancing the activity of the cyst's internal factors, which can promote the formation and growth of cysts; and any infection in any part of the body will enter the kidneys through the blood and affect the cysts. If the cyst is infected, in addition to aggravating the clinical symptoms, it will also cause the cyst to grow further and aggravate kidney damage. Common infections include upper respiratory tract infections (including colds), urinary tract infections, gastrointestinal tract infections, skin infections, traumatic infections, instrument infections, etc. That is, whether it is bacterial infection or viral infection, it can have a great impact on cysts.