What is protein interaction?

Protein is an important concept in life, because food is full of protein, and the human body needs a lot of protein every day to maintain life. With the advancement of modern science and technology, people's research on protein is becoming more and more in-depth, and microscopic protein research results have emerged. For example, studying protein interaction is a relatively important topic. Let's take a look at what protein interaction is.

Protein-protein interactions constitute a major component of the cellular biochemical reaction network and are of great significance in regulating cells and their signals.

Protein interaction studies can be divided into two categories according to the experimental purpose: one is to verify whether there is an interaction between two proteins, and the other is to screen for interacting proteins of a protein of interest.

(1) The nature of the probe protein and the source of the interacting protein: The nature of the probe protein: it can be a full-length protein, an interaction-related domain, or even a smaller biologically active fragment synthesized by chemical synthesis. Sources of interacting proteins: Cell lines that are known to endogenously express the probe protein are ideal experimental materials for searching for proteins that interact with it.