Side effects of nifedipine tablets

Nifedipine tablets are a relatively common drug in clinical medicine, mainly used to treat diseases such as angina pectoris and hypertension. Of course, if you want to fully exert the effect of nifedipine tablets and enable patients to recover their health as soon as possible while taking the medicine safely, you need to use the medicine according to certain usage and dosage. However, nifedipine tablets also have certain side effects. The following is a detailed introduction to the relevant knowledge of nifedipine tablets.

1. Main effects

1. Angina pectoris: variant angina; unstable angina; chronic stable angina.

2. Hypertension (alone or in combination with other antihypertensive drugs).

2. Usage and Dosage

1. The dose of nifedipine should be gradually adjusted according to the patient's tolerance and control of angina pectoris. Overdose of nifedipine may cause hypotension.

2. Start with a small dose. The general starting dose is 10 mg/time, 3 times a day. The commonly used maintenance dose is 10-20 mg/time, 3 times a day. For some patients with obvious coronary artery spasm, 20-30 mg/time, 3-4 times a day can be used. The maximum dose should not exceed 120 mg/day. If the condition is urgent, 10 mg/time can be chewed or taken sublingually. The decision to give the drug again can be made based on the patient's response to the drug.

3. Usually the dose is adjusted over 7-14 days. If the patient has significant symptoms and the condition is urgent, the dose adjustment period can be shortened.

3. Adverse Reactions

Common post-dose symptoms include peripheral edema (peripheral edema is dose-related, with an incidence of 4% when taking 60 mg/day and 12.5% ​​when taking 120 mg/day); dizziness; headache; nausea; fatigue and facial flushing (10%). Transient hypotension (5%) usually does not require drug discontinuation (transient hypotension is dose-related, with an incidence of 2% at doses <60 mg/day and 5% at doses of 120 mg/day).

Angina pectoris may occur in some patients, which may be related to hypotension reaction. Other symptoms include palpitations, nasal congestion, chest tightness, shortness of breath, constipation, diarrhea, gastrointestinal cramps, abdominal distension, skeletal muscle inflammation, joint stiffness, muscle spasms, mental tension, tremors, nervousness, sleep disorders, blurred vision, and imbalance, etc. (2%).