The role and efficacy of b12 injection

The human body needs many nutrients, especially various vitamins, which are indispensable. Although vitamin B12 is not familiar to everyone, it is also an important nutrient in the human body. If anemia occurs, vitamin B12 should be supplemented in time. The effects and functions of B12 injections are manifested in several aspects. It can effectively prevent anemia, prevent Alzheimer's disease, etc.

Vitamin B12 is the only water-soluble vitamin essential to the human body that contains metal ions. When vitamin B12 is deficient, the hematopoietic system and nervous system are mainly affected. Through the study of its physiological functions, we know that vitamin B12 is an important nutrient for the human body. It participates in various metabolisms in the body. It can also effectively prevent pernicious anemia, Alzheimer's disease, depression and other diseases, and plays an important role in maintaining human health.

In the body's metabolism, vitamin B12 mainly has the following functions: 1. Vitamin B12 can promote the biosynthesis of amino acids, especially methionine and glutamate, and therefore plays an important role in the synthesis of various proteins. Therefore, vitamin B12 is essential for growing infants and young children. 2. Because it promotes the synthesis of genetic material in the body, it can promote the development and maturation of red blood cells, thereby ensuring that the body's hematopoietic function is in a normal state and avoiding the occurrence of pernicious anemia.

Precautions

1. It can cause allergic reactions or even anaphylactic shock and should not be abused.

2. If conditions permit, blood vitamin B12 concentration should be monitored during medication.

3. Gout patients may develop hyperuricemia when using this product.

4. In the treatment of megaloblastic anemia, it is advisable to check blood potassium within the first 48 hours to prevent hypokalemia.

Pharmacology and Toxicology

This product is an anti-anemia drug. Vitamin B12 participates in methyl conversion and folic acid metabolism in the body, promoting the conversion of 5-methyltetrahydrofolate into tetrahydrofolate. When it is deficient, it leads to DNA synthesis disorders and affects the maturation of red blood cells. This product also promotes the conversion of methylmalonic acid into succinic acid and participates in the tricarboxylic acid cycle. This effect is related to the synthesis of myelin lipids and the maintenance of the integrity of myelinated nerve fiber function. The nerve damage caused by vitamin B12 deficiency may be related to this.

Pharmacokinetics

It is absorbed rapidly and completely after intramuscular injection, with the blood concentration reaching its peak in about 1 hour. It is widely distributed in the body, but is mainly stored in the liver, with a total storage capacity of 4 to 5 mg in adults. Most of it is excreted through the kidneys within 8 hours. The larger the dose, the more is excreted.