The role of furosemide

We may not understand what furosemide means, but if we change it to diuretic, I think everyone will understand it. Urinating is an essential process of our body's metabolism. However, if some patients have kidney problems or other reasons that lead to loss of excretion function, the doctor will use the furosemide method on the patients. There are many ways to use furosemide, either through medication or other auxiliary tools. So what does furosemide do? How should furosemide be administered specifically?

The generic name of furosemide is furosemide, a diuretic suitable for patients with grade 1 and 2 hypertension, especially those with hypertension in the elderly or with concurrent heart failure. It is clinically used to treat cardiac and renal edema, cirrhosis ascites, and hypotension. Its diuretic effect is rapid and powerful.

It is clinically used to treat cardiac edema, renal edema, ascites due to cirrhosis, peripheral edema caused by functional disorders or vascular disorders, and can promote the excretion of upper urethral stones. It has a rapid and powerful diuretic effect and is often used for seriously ill patients who are ineffective with other diuretics. Due to the obvious loss of water and electrolytes, it is not suitable for routine use. Intravenous administration (20-80 mg) can treat pulmonary edema and cerebral edema. It can be used to accelerate the excretion of poisons in case of drug poisoning.

Usage Edit

1. Intramuscular or intravenous injection: 20 mg each time, once every other day, or 1 to 2 times a day if necessary. The daily dose can be increased to 120 mg as needed. The intravenous injection must be slow and should not be mixed with other drugs for injection. Children should use a reduced dosage. 2. Oral: Initially 40 mg per day, which can be increased to 80-120 mg per day as needed. When the daily dose exceeds 40 mg, it can be taken in divided doses every 4 hours. The initial oral dose for children is 1-2 mg per kilogram of body weight, and can be increased as appropriate. The diuretic effect disappears after long-term (7 to 10 days) use of the drug, so if long-term use is required, intermittent therapy should be adopted: administer the drug for 1 to 3 days and stop the drug for 2 to 4 days.

The following points should be noted:

1. Adverse reactions such as mild nausea, diarrhea, drug rash, itching, blurred vision, etc. may occur. Sometimes, standing dizziness, weakness, tiredness, muscle cramps, thirst may occur. A small number of patients have leukopenia, and some patients have thrombocytopenia, erythema multiforme, and orthostatic hypotension. Long-term use can cause gastric and duodenal ulcers.

2. Because it can reduce the excretion of uric acid, repeated use can cause hyperuricemia, and long-term use in some patients can cause acute gout.

3. It may increase blood sugar in diabetic patients after use; although its effect of increasing blood sugar is much weaker than that of thiazide diuretics, it may still increase blood sugar when used in combination with hypoglycemic drugs.

4. Due to the rapid and strong diuretic effect, it is important to pay attention to the initial dose to prevent excessive diuresis, which may cause dehydration and electrolyte imbalance.

5. After taking the drug, hepatitis patients may easily develop hepatic coma due to excessive loss of electrolytes (especially potassium ions).

6. When taking large amounts of medication for a long time, you should pay attention to checking the electrolyte concentration in the blood. Patients with refractory edema are particularly prone to symptoms of hypokalemia. When using digitalis or potassium-excreting steroid hormones at the same time, they should pay more attention to supplementing potassium salts.